[作为影响异生物代谢和毒性因素的大鼠体内维生素A摄入量]
[Body vitamin A allowance of rats as a factor affecting the metabolism and toxicity of xenobiotics].
作者信息
Pentiuk A A, Gutsol V I, Lutsiuk N B, Bogdanov N G
出版信息
Farmakol Toksikol. 1987 Sep-Oct;50(5):51-4.
PMID:3691780
Abstract
In experiments on albino rats it was shown that vitamin A deficiency delays and its excess enhances biotransformation of aminopyrine and benzoic acid. Vitamin A excess exerted the protective effect in acute intoxication with bromobenzene, cyclophosphamide and dimethylnitrosamine.
摘要
在对白化大鼠的实验中发现，维生素A缺乏会延迟，而其过量则会增强氨基比林和苯甲酸的生物转化。维生素A过量对溴苯、环磷酰胺和二甲基亚硝胺急性中毒具有保护作用。
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