• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Understanding how diagnostics influence antimicrobial decision-making is key to successful clinical trial design.

作者信息

Rawson Timothy M, Moore Luke S P

机构信息

National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, London, United Kingdom; Centre for Antimicrobial Optimisation, Imperial College London, Hammersmith Hospital, London, United Kingdom; David Price Evan's Group in Infectious Diseases and Global Health, Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, United Kingdom.

National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, London, United Kingdom; Chelsea & Westminster NHS Foundation Trust, London, United Kingdom; North West London Pathology, Imperial College Healthcare NHS Trust, London, United Kingdom.

出版信息

Clin Microbiol Infect. 2023 Jun;29(6):666-669. doi: 10.1016/j.cmi.2023.03.010. Epub 2023 Mar 12.

DOI:10.1016/j.cmi.2023.03.010
PMID:36918143
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10008184/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b80/10008184/09a551433651/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b80/10008184/09a551433651/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b80/10008184/09a551433651/gr1_lrg.jpg

相似文献

1
Understanding how diagnostics influence antimicrobial decision-making is key to successful clinical trial design.了解诊断如何影响抗菌药物决策是成功进行临床试验设计的关键。
Clin Microbiol Infect. 2023 Jun;29(6):666-669. doi: 10.1016/j.cmi.2023.03.010. Epub 2023 Mar 12.
2
Multiplex PCR point of care testing versus routine, laboratory-based testing in the treatment of adults with respiratory tract infections: a quasi-randomised study assessing impact on length of stay and antimicrobial use.多重聚合酶链反应即时检测与常规实验室检测在成人呼吸道感染治疗中的比较：一项评估对住院时间和抗菌药物使用影响的半随机研究
BMC Infect Dis. 2017 Oct 10;17(1):671. doi: 10.1186/s12879-017-2784-z.
3
Impact of multiplex PCR on antimicrobial treatment in febrile neutropenia: a randomized controlled study.多重聚合酶链反应对发热性中性粒细胞减少症抗菌治疗的影响：一项随机对照研究。
Med Microbiol Immunol. 2015 Oct;204(5):585-92. doi: 10.1007/s00430-014-0385-7. Epub 2015 Jan 9.
4
Evaluation of the BioFire Blood Culture Identification 2 panel and impact on patient management and antimicrobial stewardship.评估生物梅里埃血培养鉴定 2 面板及其对患者管理和抗菌药物管理的影响。
Pathology. 2021 Dec;53(7):889-895. doi: 10.1016/j.pathol.2021.02.016. Epub 2021 Jun 11.
5
Examining the clinical impact of rapid multiplex polymerase chain reaction-based diagnostic testing for bloodstream infections in a national cohort of the Veterans Health Administration.在退伍军人健康管理局的全国队列中，检查基于快速多重聚合酶链反应的诊断检测对血流感染的临床影响。
Pharmacotherapy. 2023 Jan;43(1):24-34. doi: 10.1002/phar.2747. Epub 2022 Dec 21.
6
Contemporary approaches to the rapid molecular diagnosis of sepsis.当代脓毒症快速分子诊断方法。
Expert Rev Mol Diagn. 2016 Nov;16(11):1201-1207. doi: 10.1080/14737159.2016.1246958. Epub 2016 Oct 21.
7
Should we treat severe sepsis with activated protein C?
Hosp Med. 2003 May;64(5):316. doi: 10.12968/hosp.2003.64.5.1771.
8
Using mathematical modeling to bridge phase 3 microbicide trials with public health decision making.
J Acquir Immune Defic Syndr. 2009 Apr 1;50(4):434-5. doi: 10.1097/QAI.0b013e31819461ab.
9
Impact on the medical decision-making process of multiplex PCR assay for respiratory pathogens.多重PCR检测呼吸道病原体对医疗决策过程的影响。
Epidemiol Infect. 2017 Oct;145(13):2766-2769. doi: 10.1017/S0950268817001029. Epub 2017 May 18.
10
Antimicrobial drug discovery.抗菌药物发现
Future Microbiol. 2011 Jun;6(6):601-2. doi: 10.2217/fmb.11.54.

引用本文的文献

1
A mixed methods evaluation of an antimicrobial prescribing clinical decision support system app.抗菌药物处方临床决策支持系统应用程序的混合方法评估
NPJ Antimicrob Resist. 2025 Aug 18;3(1):71. doi: 10.1038/s44259-025-00146-8.
2
Towards a holistic approach to pulmonary infections. Insights from the Sixth Annual Meeting of Spanish Experts 2024.迈向肺部感染的整体治疗方法。来自2024年西班牙专家第六届年会的见解。
Rev Esp Quimioter. 2025 Mar 27;38(3):152-186. doi: 10.37201/req/017.2025.
3
Metagenomic next-generation sequencing, instead of procalcitonin, could guide antibiotic usage in patients with febrile acute necrotizing pancreatitis: a multicenter, prospective cohort study.

本文引用的文献

1
Respiratory multiplex PCR and procalcitonin to reduce antibiotic exposure in severe SARS-CoV-2 pneumonia: a multicentre randomized controlled trial.呼吸多重聚合酶链反应和降钙素原减少严重 SARS-CoV-2 肺炎抗生素暴露：一项多中心随机对照试验。
Clin Microbiol Infect. 2023 Jun;29(6):734-743. doi: 10.1016/j.cmi.2023.01.009. Epub 2023 Jan 18.
2
Negative predictive value of procalcitonin to rule out bacterial respiratory co-infection in critical covid-19 patients.降钙素原对排除危重症 COVID-19 患者细菌合并呼吸道感染的阴性预测值。
J Infect. 2022 Oct;85(4):374-381. doi: 10.1016/j.jinf.2022.06.024. Epub 2022 Jun 30.
3
宏基因组下一代测序，而非降钙素原，可指导发热性急性坏死性胰腺炎患者的抗生素使用：一项多中心前瞻性队列研究。
Int J Surg. 2024 May 1;110(5):2721-2729. doi: 10.1097/JS9.0000000000001162.
4
Management of Bacterial and Fungal Infections in the ICU: Diagnosis, Treatment, and Prevention Recommendations.重症监护病房中细菌和真菌感染的管理：诊断、治疗及预防建议
Infect Drug Resist. 2023 May 4;16:2709-2726. doi: 10.2147/IDR.S390946. eCollection 2023.
The EUCAST rapid disc diffusion method for antimicrobial susceptibility testing directly from positive blood culture bottles.
EUCAST 快速纸片扩散法直接从阳性血培养瓶中进行抗菌药物敏感性试验。
J Antimicrob Chemother. 2020 Apr 1;75(4):968-978. doi: 10.1093/jac/dkz548.
4
Clinical Utility of Advanced Microbiology Testing Tools.临床应用的高级微生物检测工具。
J Clin Microbiol. 2019 Aug 26;57(9). doi: 10.1128/JCM.00495-19. Print 2019 Sep.
5
Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials.降钙素原指导抗生素治疗对感染和脓毒症 ICU 患者临床结局的影响：随机试验的患者水平荟萃分析。
Crit Care. 2018 Aug 15;22(1):191. doi: 10.1186/s13054-018-2125-7.
6
Clinical Utility and Measurement of Procalcitonin.降钙素原的临床应用与检测
Clin Biochem Rev. 2017 Apr;38(2):59-68.
7
Procalcitonin-guided diagnosis and antibiotic stewardship revisited.降钙素原指导下的诊断与抗生素管理再探讨。
BMC Med. 2017 Jan 24;15(1):15. doi: 10.1186/s12916-017-0795-7.
8
Mapping the decision pathways of acute infection management in secondary care among UK medical physicians: a qualitative study.绘制英国内科医生在二级医疗中急性感染管理的决策路径：一项定性研究。
BMC Med. 2016 Dec 12;14(1):208. doi: 10.1186/s12916-016-0751-y.
9
Randomized Trial of Rapid Multiplex Polymerase Chain Reaction-Based Blood Culture Identification and Susceptibility Testing.基于快速多重聚合酶链反应的血培养鉴定及药敏试验的随机试验
Clin Infect Dis. 2015 Oct 1;61(7):1071-80. doi: 10.1093/cid/civ447. Epub 2015 Jul 20.
10
A PCT algorithm for discontinuation of antibiotic therapy is a cost-effective way to reduce antibiotic exposure in adult intensive care patients with sepsis.一种用于停用抗生素治疗的序贯器官衰竭评估（PCT）算法是减少脓毒症成年重症监护患者抗生素暴露的一种经济有效的方法。
J Med Econ. 2015;18(11):944-53. doi: 10.3111/13696998.2015.1064934. Epub 2015 Jul 20.