Department of Orthopedic Surgery, NYU Langone Health, 301 E 17th St, New York, NY, 10003, USA.
Adult Reconstructive Division, Anne Arundel Medical Center, Annapolis, MD, USA.
Arch Orthop Trauma Surg. 2023 Sep;143(9):5993-5999. doi: 10.1007/s00402-023-04830-0. Epub 2023 Mar 15.
Reduced bone mineral density (BMD) and disruption of normal bony architecture are the characteristics of osteopenia and osteoporosis and in patients undergoing total hip arthroplasty (THA) may cause failure of trabecular ingrowth. The purpose of this study is to evaluate the impact of reduced BMD on outcomes following primary elective THA.
A retrospective chart review of 650 elective THAs with a DEXA scan in their electronic health record (EHR) from 2011 to 2020 was conducted at an urban, academic center and a regional, health center. Patients were separated into three cohorts based on their t-score and the World Health Organizations definitions: normal (t-score ≥ - 1), osteopenia (t-score < - 1.0 and > - 2.5), and osteoporosis (t-score ≤ - 2.5). Demographic and outcome data were assessed. Subsidence was assessed for patients with non-cemented THAs. Regression models were used to account for demographic differences.
650 elective THAs, of which only 11 were cemented, were included in the study. Patients with osteopenia and osteoporosis were significantly older than those without (p = 0.002 and p < 0.0001, respectively) and had a lower BMI (p < 0.0001 and p < 0.0001, respectively). PFx was significantly greater in patients with osteoporosis when compared to those with normal BMD (6.5% vs. 1.0%; p = 0.04). No such difference was found between osteoporotic and osteopenic patients. The revision rate was significantly higher for osteoporotic patients than osteopenic patients (7.5% vs. 1.5%; p = 0.04). No such difference was found between the other comparison groups.
Patients with osteoporosis were older with reduced BMI and had increased PFx after non-cemented elective THA. Understanding this can help surgeons formulate an appropriate preoperative plan for the treatment of patients with osteoporotic bone undergoing elective THA.
骨密度降低(BMD)和正常骨结构破坏是骨质疏松症和骨质疏松症的特征,在接受全髋关节置换术(THA)的患者中,可能导致小梁内生长失败。本研究旨在评估原发性选择性 THA 后 BMD 降低对结果的影响。
对 2011 年至 2020 年在城市学术中心和地区卫生中心的电子健康记录(EHR)中进行 DEXA 扫描的 650 例选择性 THA 进行回顾性图表审查。根据 t 评分和世界卫生组织的定义,将患者分为三组:正常(t 评分≥-1)、骨质疏松症(t 评分<-1.0 和>-2.5)和骨质疏松症(t 评分≤-2.5)。评估人口统计学和结果数据。对非骨水泥 THA 患者进行下沉评估。使用回归模型来解释人口统计学差异。
本研究共纳入 650 例选择性 THA,其中仅 11 例为骨水泥固定。骨质疏松症和骨质疏松症患者明显比无骨质疏松症患者年龄大(p=0.002 和 p<0.0001),体重指数(BMI)较低(p<0.0001 和 p<0.0001)。与正常 BMD 相比,骨质疏松症患者的 PFx 显著更大(6.5%比 1.0%;p=0.04)。骨质疏松症和骨质疏松症患者之间没有发现这种差异。与骨质疏松症患者相比,骨质疏松症患者的翻修率明显更高(7.5%比 1.5%;p=0.04)。在其他比较组中没有发现这种差异。
骨质疏松症患者年龄较大,BMI 降低,非骨水泥选择性 THA 后 PFx 增加。了解这一点可以帮助外科医生为接受骨质疏松性骨选择性 THA 的患者制定适当的术前治疗计划。