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2016-2018 年撒哈拉以南非洲部分国家扩大艾滋病毒病毒载量检测的进展。

Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016-2018.

机构信息

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Division of Global HIV and TB, Center for Global Health, CDC, Abidjan, Côte d'Ivoire.

出版信息

PLoS One. 2023 Mar 15;18(3):e0282652. doi: 10.1371/journal.pone.0282652. eCollection 2023.

Abstract

INTRODUCTION

We assessed progress in HIV viral load (VL) scale up across seven sub-Saharan African (SSA) countries and discussed challenges and strategies for improving VL coverage among patients on anti-retroviral therapy (ART).

METHODS

A retrospective review of VL testing was conducted in Côte d'Ivoire, Kenya, Lesotho, Malawi, Namibia, Tanzania, and Uganda from January 2016 through June 2018. Data were collected and included the cumulative number of ART patients, number of patients with ≥ 1 VL test result (within the preceding 12 months), the percent of VL test results indicating viral suppression, and the mean turnaround time for VL testing.

RESULTS

Between 2016 and 2018, the proportion of PLHIV on ART in all 7 countries increased (range 5.7%-50.2%). During the same time period, the cumulative number of patients with one or more VL test increased from 22,996 to 917,980. Overall, viral suppression rates exceeded 85% for all countries except for Côte d'Ivoire at 78% by June 2018. Reported turnaround times for VL testing results improved in 5 out of 7 countries by between 5.4 days and 27.5 days.

CONCLUSIONS

These data demonstrate that remarkable progress has been made in the scale-up of HIV VL testing in the seven SSA countries.

摘要

简介

我们评估了撒哈拉以南非洲(SSA)七个国家的 HIV 病毒载量(VL)检测情况,并讨论了提高抗逆转录病毒治疗(ART)患者 VL 覆盖率的挑战和策略。

方法

对科特迪瓦、肯尼亚、莱索托、马拉维、纳米比亚、坦桑尼亚和乌干达 2016 年 1 月至 2018 年 6 月的 VL 检测情况进行了回顾性分析。收集了数据,包括累计接受 ART 的患者人数、在过去 12 个月内至少进行了一次 VL 检测的患者人数、VL 检测结果表明病毒抑制的比例,以及 VL 检测的平均周转时间。

结果

2016 年至 2018 年间,所有 7 个国家接受 ART 的 PLHIV 比例均有所增加(范围为 5.7%-50.2%)。同期,至少进行过一次 VL 检测的患者累计人数从 22996 人增加到 917980 人。除科特迪瓦外,所有国家的病毒抑制率均超过 85%,而科特迪瓦截至 2018 年 6 月的病毒抑制率为 78%。7 个国家中有 5 个国家的 VL 检测结果报告周转时间缩短了 5.4 至 27.5 天。

结论

这些数据表明,在撒哈拉以南非洲七个国家中,HIV VL 检测的普及取得了显著进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e3f/10016655/ab5be392092e/pone.0282652.g001.jpg

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