Alnimr Amani
Department of Medical Microbiology, King Fahad Hospital of the University, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Infect Drug Resist. 2023 Mar 9;16:1339-1344. doi: 10.2147/IDR.S403830. eCollection 2023.
. is an emerging, non-fermentative Gram-negative rod that demonstrates multidrug resistance. Herein, four cases of bloodstream infections (BSI) caused by are presented. All the cases had comorbidities that predisposed them to this opportunistic infection. The microbiological assessment showed carbapenemase genes carried out in two strains with minimal inhibitory concentrations > 32 μg/mL to imipenem and meropenem. Fluoroquinolones and trimethoprim-sulphamethoxazole were the most potent agents showing activity against 3/4 strains (75%), although treatment should be susceptibility-dependent for each strain. This case series highlights the possibility of co-infection by a rare organism during the COVID-19 pandemic and the importance of the readiness of diagnostic laboratories to support the diagnosis of uncommon pathogens.
. 是一种新兴的、非发酵革兰氏阴性杆菌，具有多重耐药性。本文介绍了4例由 引起的血流感染（BSI）病例。所有病例都有合并症，使他们易患这种机会性感染。微生物学评估显示，两株菌株携带碳青霉烯酶基因，对亚胺培南和美罗培南的最低抑菌浓度>32μg/mL。氟喹诺酮类和甲氧苄啶-磺胺甲恶唑是对3/4菌株（75%）显示活性的最有效药物，尽管治疗应根据每个菌株的药敏情况而定。该病例系列突出了在COVID-19大流行期间罕见病原体合并感染的可能性以及诊断实验室做好支持罕见病原体诊断准备的重要性。
