Knoedler Samuel, Matar Dany Y, Knoedler Leonard, Obed Doha, Haug Valentin, Gorski Sabina M, Kim Bong-Sung, Kauke-Navarro Martin, Kneser Ulrich, Panayi Adriana C, Orgill Dennis P, Hundeshagen Gabriel
Department of Plastic, Hand and Reconstructive Surgery, University Hospital Regensburg, Regensburg, Germany.
Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Front Surg. 2023 Feb 27;10:1131293. doi: 10.3389/fsurg.2023.1131293. eCollection 2023.
Burn injuries are associated with significant morbidity, often necessitating surgical management. Older patients are more prone to burns and more vulnerable to complications following major burns. While the relationship between senescence and major burns has already been thoroughly investigated, the role of age in minor burns remains unclear. To better understand differences between elderly and younger patients with predominantly minor burns, we analyzed a multi-institutional database.
We reviewed the 2008-2020 ACS-NSQIP database to identify patients who had suffered burns according to ICD coding and underwent initial burn surgery.
We found 460 patients, of which 283 (62%) were male and 177 (38%) were female. The mean age of the study cohort was 46 ± 17 years, with nearly one-fourth ( = 108; 23%) of all patients being aged ≥60 years. While the majority ( = 293; 64%) suffered from third-degree burns, 22% ( = 99) and 15% ( = 68) were diagnosed with second-degree burns and unspecified burns, respectively. An average operation time of 46 min, a low mortality rate of 0.2% ( = 1), a short mean length of hospital stay (1 day), and an equal distribution of in- and outpatient care (51%, = 234 and 49%, = 226, respectively) indicated that the vast majority of patients suffered from minor burns. Patients aged ≥60 years showed a significantly prolonged length of hospital stay (<0.0001) and were significantly more prone to non-home discharge (<0.0001). In univariate analysis, advanced age was found to be a predictor of surgical complications ( = 0.001) and medical complications ( = 0.0007). Elevated levels of blood urea nitrogen (>0.0001), creatinine (>0.0001), white blood cell count (=0.02), partial thromboplastin time ( = 0.004), and lower levels of albumin ( = 0.0009) and hematocrit (>0.0001) were identified as risk factors for the occurrence of any complication. Further, complications were more frequent among patients with lower body burns.
In conclusion, patients ≥60 years undergoing surgery for predominantly minor burns experienced significantly more complications. Minor lower body burns correlated with worse outcomes and a higher incidence of adverse events. Decreased levels of serum albumin and hematocrit and elevated values of blood urea nitrogen, creatinine, white blood count, and partial thromboplastin time were identified as predictive risk factors for complications.
烧伤会导致严重的发病率,常常需要手术治疗。老年患者更容易发生烧伤,且在严重烧伤后更容易出现并发症。虽然衰老与严重烧伤之间的关系已经得到了充分研究,但年龄在轻度烧伤中的作用仍不明确。为了更好地了解以轻度烧伤为主的老年患者和年轻患者之间的差异,我们分析了一个多机构数据库。
我们回顾了2008 - 2020年美国外科医师学会国家外科质量改进计划(ACS - NSQIP)数据库,以识别根据国际疾病分类(ICD)编码遭受烧伤并接受初次烧伤手术的患者。
我们共找到460例患者,其中男性283例(62%),女性177例(38%)。研究队列的平均年龄为46±17岁,所有患者中近四分之一(n = 108;23%)年龄≥60岁。虽然大多数患者(n = 293;64%)为三度烧伤,但分别有22%(n = 99)和15%(n = 68)被诊断为二度烧伤和未明确烧伤程度的烧伤。平均手术时间为46分钟,死亡率低至0.2%(n = 1),平均住院时间短(1天),门诊和住院治疗分布均衡(分别为51%,n = 234和49%,n = 226),这表明绝大多数患者为轻度烧伤。年龄≥60岁的患者住院时间显著延长(P < 0.0001),且明显更倾向于非家庭出院(P < 0.0001)。在单因素分析中,高龄被发现是手术并发症(P = 0.001)和医疗并发症(P = 0.0007)的预测因素。血尿素氮水平升高(P < 0.0001)、肌酐水平升高(P < 0.0001)、白细胞计数升高(P = 0.02)、部分凝血活酶时间延长(P = 0.004)以及白蛋白水平降低(P = 0.0009)和血细胞比容降低(P < 0.0001)被确定为发生任何并发症的危险因素。此外,下肢烧伤患者的并发症更为常见。
总之,年龄≥60岁且以轻度烧伤为主而接受手术的患者并发症明显更多。下肢轻度烧伤与更差的预后和更高的不良事件发生率相关。血清白蛋白和血细胞比容水平降低以及血尿素氮、肌酐、白细胞计数和部分凝血活酶时间值升高被确定为并发症的预测性危险因素。