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膝关节孤立性巨大神经纤维瘤:病例报告

Solitary giant neurofibroma of the knee: a case report.

作者信息

Lachkar Adnane, El Farhaoui Amine, Najib Abdeljaouad, Yacoubi Hicham

机构信息

Department of Orthopedic Surgery B, Hospital University Center Mohammed VI, Oujda, Morocco.

出版信息

Ann Med Surg (Lond). 2023 Mar 9;85(3):470-472. doi: 10.1097/MS9.0000000000000181. eCollection 2023 Mar.

Abstract

UNLABELLED

Solitary neurofibroma is a rare tumor that occurs particularly in the head and trunk. It is mostly small and rarely exceeds 2 cm.

CASE REPORT

A 61-year-old female patient complained about an increasingly extended mass with pain in the right knee for about 14 months. Physical examination reveals a big, solid mass in front of the medial condyle, measuring about 14×12 cm. Tinel's sign was positive on mass percussion. MRI showed a well-circumscribed oval mass with low signal on T1 and high signal on T2-weighted images. A surgical biopsy was performed, and immunohistochemistry confirmed the diagnosis of solitary neurofibroma. Surgical excisions were performed with good outcomes.

DISCUSSION

A giant solitary neurofibroma is exceptional. The knee location is even rarer. Immunohistochemistry is the only way to confirm the diagnosis.

CONCLUSION

Giant neurofibromas need a complete surgical excision. Until today, there were no other alternative therapies for these tumors.

摘要

摘要

孤立性神经纤维瘤是一种罕见肿瘤,尤其好发于头颈部和躯干。肿瘤大多较小,很少超过2厘米。

病例报告

一名61岁女性患者因右膝肿物逐渐增大伴疼痛就诊,病程约14个月。体格检查发现内侧髁前方有一巨大实性肿物,大小约14×12厘米。肿物叩击试验(Tinel征)阳性。磁共振成像(MRI)显示为边界清晰的椭圆形肿物,T1加权像呈低信号,T2加权像呈高信号。行手术活检,免疫组化确诊为孤立性神经纤维瘤。手术切除后效果良好。

讨论

巨大孤立性神经纤维瘤较为罕见,发生于膝关节部位的更是少见。免疫组化是确诊的唯一方法。

结论

巨大神经纤维瘤需要完整手术切除。目前,针对这类肿瘤尚无其他替代治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79a5/10010813/8bb7df600b1f/ms9-85-502-g001.jpg

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