Department of Orthopedics, The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang Province, P. R. China.
Sci Prog. 2021 Jan-Mar;104(1):368504211004269. doi: 10.1177/00368504211004269.
Neurofibroma is a rare nerve sheath tumor of neuroectodermal origin, especially the huge and isolated neurofibroma located in the inguinal region. To our knowledge, no such case has previously been reported. We report a case of 34-year-old male patient with a 4-year history of progressive enlargement of the medial root mass in his left thigh with sitting and standing disorders along with pain. The tumor was completely removed by operation, and pathological diagnosis showed neurofibroma. There was no obvious neurologic defect after surgery, and no recurrence tendency was found in the follow-up of 2 years. For a large solitary mass with slow growth and no malignant clinical manifestations for a long time, clinicians cannot rule out the hypothetical diagnosis of neurofibroma, even though its growth site is very rare, such as this case of a huge tumor located in the groin. For neurogenic tumors, early operation should be performed, and the prognosis of patients after tumor resection is excellent.
神经纤维瘤是一种罕见的神经鞘起源的肿瘤,特别是位于腹股沟区域的巨大孤立性神经纤维瘤。据我们所知,以前没有报道过这种病例。我们报告了 1 例 34 岁男性患者,其病史为 4 年,左侧大腿内侧根部肿块逐渐增大,伴有坐位和站位障碍及疼痛。肿瘤通过手术完全切除,病理诊断为神经纤维瘤。术后无明显神经功能缺损,随访 2 年均未见复发倾向。对于生长缓慢且无恶性临床表现的巨大孤立性肿块,临床医生不能排除神经纤维瘤的假设诊断,即使其生长部位非常罕见,如本例位于腹股沟的巨大肿瘤。对于神经源性肿瘤,应尽早进行手术,患者在肿瘤切除后的预后极好。