Maidarti Mila, Garinasih Prini D, Anggraeni Tricia D
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Indonesia.
Yasmin IVF Clinic, Dr. Cipto Mangunkusumo General Hospital.
Ann Med Surg (Lond). 2023 Feb 13;85(3):427-430. doi: 10.1097/MS9.0000000000000146. eCollection 2023 Mar.
Ovarian tumor is a rare condition in pediatrics. Due to the improvement in surgical techniques and chemotherapy in recent years, it is currently possible to preserve fertility in selected cases of patients who desire motherhood.
We present a case of pregnancy following conservative surgery and complete chemotherapy for ovarian dysgerminoma stage IIA. A 16-year-old female presented with complaints of abdominal mass and discomfort. Histopathological examination displayed dysgerminoma arising from the right ovary. Conservative treatment with right salpingo-oophorectomy and six cycles of chemotherapy was performed. Within 2 years following the surgery, the patient conceived and did not indicate tumor recurrence.
Dysgerminoma is the most common ovarian malignant germ cell tumor and usually affects women at a young age. Conservative surgery followed by chemotherapy is the treatment of choice, particularly in young patients with a strong desire to have a family. Conservative fertility-sparing surgery does not have inferior outcomes in terms of survival or recurrence. It is possible that in certain cases, patients previously treated for ovarian cancer may retain their fertility, thereby improving their quality of life.
Most patients with dysgerminoma can be treated with the maintenance of normal reproductive function. Reassurance regarding the high probability of conceiving and having normal children after conservative surgery and chemotherapy should be informed to the patient and family.
卵巢肿瘤在儿科是一种罕见病症。由于近年来手术技术和化疗的进步，目前在某些有生育意愿的患者中保留生育能力成为可能。
我们报告一例卵巢无性细胞瘤IIA期患者在接受保守手术及完整化疗后怀孕的病例。一名16岁女性因腹部肿块和不适前来就诊。组织病理学检查显示肿瘤起源于右侧卵巢，为无性细胞瘤。对其实施了右侧输卵管卵巢切除术及六个周期的化疗进行保守治疗。术后两年内，该患者成功受孕且未出现肿瘤复发迹象。
无性细胞瘤是最常见的卵巢恶性生殖细胞肿瘤，通常影响年轻女性。首选治疗方法是保守手术联合化疗，尤其是对于有强烈生育意愿的年轻患者。保留生育功能的保守手术在生存率和复发率方面并无劣势。在某些情况下，先前接受过卵巢癌治疗的患者有可能保留生育能力，从而提高生活质量。
大多数无性细胞瘤患者可以在维持正常生殖功能的情况下接受治疗。应告知患者及其家属，保守手术和化疗后成功受孕并生育正常孩子的可能性很大，以此给予他们安心。
