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传统健身运动对骨质疏松症患者骨与软骨组织的作用及调控机制:一项叙述性综述

The role and regulation mechanism of Chinese traditional fitness exercises on the bone and cartilage tissue in patients with osteoporosis: A narrative review.

作者信息

Sun Weibo, Zhang Xin-An, Wang Zhuo

机构信息

College of Exercise and Health, Shenyang Sport University, Shenyang, China.

出版信息

Front Physiol. 2023 Feb 28;14:1071005. doi: 10.3389/fphys.2023.1071005. eCollection 2023.

Abstract

Osteoporosis (ops) is a systemic degenerative bone disease characterized by bone mass reduction, bone mineral density loss, bone microstructure destruction, bone fragility, and increased fracture susceptibility. Thus far, drug therapy is the main method used to prevent and treat osteoporosis. However, long-term drug treatment will inevitably lead to drug resistance and certain side effects. In response, rehabilitation treatment is generally recommended, which involves drug supplementation combined with the treatment. A Chinese traditional fitness exercise is an organic combination of sports and traditional Chinese medicine with a series of advantages such as being safe, convenient, non-toxic, and harmless. Hence, it is one of the rehabilitation methods widely used in clinical practice. By searching the CNKI, PubMed, Web of Science, Embase, Cochrane Library, and other relevant databases, our research clarifies the current situation of four kinds of Chinese traditional fitness exercises widely used in clinical practice, namely, Taijiquan, Baduanjin, Wuqinxi, and Yijin Jing. In addition, the molecular mechanism of osteoporosis is summarized in this study. Based on the research, Chinese traditional fitness exercises are expected to directly stimulate the bone through a mechanical load to improve bone density. Moderate and regular traditional Chinese fitness exercises also improve osteoporosis by regulating the endocrine system with the secretion of hormones and factors such as estrogen and irisin, which are beneficial for bone formation. Finally, the purpose of promoting bone formation, reducing bone loss, and preventing and treating osteoporosis is achieved. The various means of Chinese traditional fitness exercises have different emphases, and the effect of improving bone density differs in various parts of the body. The exercisers may choose the exercise flexibly based on their own needs. Chinese traditional fitness exercises can improve the bone density of the exercisers and relieve pain, improve balance, and regulate the psychological state. Consequently, it is worth promoting to be applied in clinical practices.

摘要

骨质疏松症是一种全身性退行性骨病,其特征为骨量减少、骨矿物质密度降低、骨微结构破坏、骨脆性增加以及骨折易感性增强。迄今为止,药物治疗是预防和治疗骨质疏松症的主要方法。然而,长期药物治疗不可避免地会导致耐药性和某些副作用。对此,一般建议采用康复治疗,即药物补充与治疗相结合。中国传统健身运动是体育与中医的有机结合,具有安全、便捷、无毒无害等一系列优点。因此,它是临床实践中广泛应用的康复方法之一。通过检索中国知网、PubMed、Web of Science、Embase、Cochrane图书馆等相关数据库,我们的研究阐明了临床实践中广泛应用的四种中国传统健身运动,即太极拳、八段锦、五禽戏和易筋经的现状。此外,本研究还总结了骨质疏松症的分子机制。基于该研究,预计中国传统健身运动可通过机械负荷直接刺激骨骼,以提高骨密度。适度且规律的中国传统健身运动还可通过调节内分泌系统,分泌雌激素和鸢尾素等对骨形成有益的激素和因子来改善骨质疏松症。最终实现促进骨形成、减少骨丢失以及预防和治疗骨质疏松症的目的。中国传统健身运动的各种方式侧重点不同,改善骨密度的效果在身体各部位也有所差异。锻炼者可根据自身需求灵活选择运动方式。中国传统健身运动可提高锻炼者的骨密度,缓解疼痛,改善平衡,并调节心理状态。因此,值得推广应用于临床实践。

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