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妊娠期格林-巴利综合征:一例保守治疗病例。

Guillain-Barré syndrome in pregnancy: A conservatively managed case.

作者信息

Fernando T N M S, Ambanwala A M A S, Ranaweera Probhodana, Kaluarachchi Athula

机构信息

Department of Obstetrics and Gynaecology, University Professorial Unit, De Soysa Maternity Hospital for Women, Colombo 8, Sri Lanka.

Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

出版信息

J Family Med Prim Care. 2016 Jul-Sep;5(3):688-690. doi: 10.4103/2249-4863.197303.

Abstract

Guillain-Barré syndrome (GBS) is an autoimmune disease. Estimated population incidence ranges from 0.62 to 2.66 cases per 100,000 person-years across all age groups. We report a case of GBS in a 22-year-old primigravida who presented at 36 weeks of the period of gestation (POG), with complaints of bilateral progressive lower limb numbness and weakness for 2 weeks duration. Magnetic resonance imaging of the brain was done to exclude other possible causes. Diagnosis of GBS was made according to the Brighton criteria, which our patient falls into Level 2. She received intensive care management. The patient improved rapidly without any specific management. She went to labor spontaneously and delivered a healthy baby with a birth weight of 2.8 kg at 38 weeks of POG. She continued to receive supportive therapy and improved significantly.

摘要

吉兰-巴雷综合征(GBS)是一种自身免疫性疾病。所有年龄组的估计人群发病率为每10万人年0.62至2.66例。我们报告一例22岁初产妇的GBS病例,该产妇在妊娠36周时就诊,主诉双侧进行性下肢麻木和无力,持续2周。进行了脑部磁共振成像以排除其他可能原因。根据布莱顿标准做出GBS诊断,我们的患者属于2级。她接受了重症监护管理。患者在未进行任何特殊治疗的情况下迅速好转。她自然临产,并在妊娠38周时产下一名健康婴儿,出生体重2.8千克。她继续接受支持性治疗并显著改善。

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本文引用的文献

1
Weakness in pregnancy - expect the unexpected.孕期虚弱——做好应对意外情况的准备。
Obstet Med. 2008 Dec;1(2):99-101. doi: 10.1258/om.2008.080011. Epub 2008 Dec 1.
2
Clinical Features of Miller-Fisher Syndrome in Pregnancy.妊娠期米勒-费雪综合征的临床特征
Case Rep Obstet Gynecol. 2015;2015:840680. doi: 10.1155/2015/840680. Epub 2015 Dec 1.
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[Epidemiology of Guillain-Barré Syndrome].[吉兰-巴雷综合征的流行病学]
Brain Nerve. 2015 Nov;67(11):1305-11. doi: 10.11477/mf.1416200300.
5
Guillain-barré syndrome in pregnancy: an unusual case.妊娠期格林-巴利综合征:一例罕见病例。
J Family Med Prim Care. 2013 Jan;2(1):90-1. doi: 10.4103/2249-4863.109965.
8
IVIG treatment and prognosis in Guillain-Barré syndrome.静脉注射免疫球蛋白治疗吉兰-巴雷综合征及预后。
J Clin Immunol. 2010 May;30 Suppl 1(Suppl 1):S74-8. doi: 10.1007/s10875-010-9407-4.

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