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前列腺癌淋巴结及骨转移的MRI脂肪分数成像

MRI fat fraction imaging of nodal and bone metastases in prostate cancer.

作者信息

Qin Cathy, Goldberg Olivia, Kakar Geetanjali, Wan Simon, Haroon Athar, Azam Aishah, Adeleke Sola

机构信息

Department of Radiology, Imperial College Healthcare NHS Trust, London, UK.

Institute of Nuclear Medicine, University College London, London, UK.

出版信息

Eur Radiol. 2023 Aug;33(8):5851-5855. doi: 10.1007/s00330-023-09527-x. Epub 2023 Mar 16.

DOI:10.1007/s00330-023-09527-x
PMID:36928564
Abstract

• Characterisation and quantification of tissue fat on MRI can be used to provide information on disease processes. • Fat in bone and lymph nodes up until recently have not been exploited for diagnostic purposes or response monitoring in prostate cancer. • Fat imaging on MRI using Dixon/PDFF sequences has the potential to add clinical value in the future but prospective data is needed.

摘要

• 磁共振成像(MRI)上组织脂肪的特征描述和定量分析可用于提供有关疾病进程的信息。

• 直到最近,骨骼和淋巴结中的脂肪尚未用于前列腺癌的诊断目的或反应监测。

• 使用狄克逊/质子密度脂肪分数(Dixon/PDFF)序列进行的MRI脂肪成像未来有可能增加临床价值,但需要前瞻性数据。

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MRI fat fraction imaging of nodal and bone metastases in prostate cancer.前列腺癌淋巴结及骨转移的MRI脂肪分数成像
Eur Radiol. 2023 Aug;33(8):5851-5855. doi: 10.1007/s00330-023-09527-x. Epub 2023 Mar 16.
2
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Preoperative multiparametric MRI of the prostate for the prediction of lymph node metastases in prostate cancer patients treated with extended pelvic lymph node dissection.前列腺癌患者行扩大盆腔淋巴结清扫术的前列腺术前多参数 MRI 预测淋巴结转移。
Eur Radiol. 2018 May;28(5):1969-1976. doi: 10.1007/s00330-017-5229-6. Epub 2017 Dec 21.
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Can whole-body magnetic resonance imaging with diffusion-weighted imaging replace Tc 99m bone scanning and computed tomography for single-step detection of metastases in patients with high-risk prostate cancer?全身磁共振弥散加权成像能否替代 Tc 99m 骨扫描和 CT 进行高危前列腺癌患者的一步法转移检测?
Eur Urol. 2012 Jul;62(1):68-75. doi: 10.1016/j.eururo.2012.02.020. Epub 2012 Feb 17.
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Shortening the acquisition time of whole-body MRI: 3D T1 gradient echo Dixon vs fast spin echo for metastatic screening in prostate cancer.缩短全身 MRI 采集时间:3D T1 梯度回波 Dixon 与快速自旋回波在前列腺癌转移筛查中的比较。
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引用本文的文献

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[A preoperative prediction model for pelvic lymph node metastasis in prostate cancer: Integrating clinical characteristics and multiparametric MRI].[一种前列腺癌盆腔淋巴结转移的术前预测模型:整合临床特征和多参数磁共振成像]
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Differentiation between normal and metastatic lymph nodes in patients with skin melanoma: Preliminary findings using a DIXON-based whole-body MRI approach.皮肤黑色素瘤患者正常淋巴结与转移淋巴结的鉴别:基于DIXON的全身MRI方法的初步研究结果
Eur J Radiol Open. 2024 Mar 19;12:100560. doi: 10.1016/j.ejro.2024.100560. eCollection 2024 Jun.

本文引用的文献

1
The future of PSMA PET and WB MRI as next-generation imaging tools in prostate cancer.PSMA PET 和 WB MRI 作为前列腺癌下一代成像工具的未来。
Nat Rev Urol. 2022 Aug;19(8):475-493. doi: 10.1038/s41585-022-00618-w. Epub 2022 Jul 4.
2
Dixon or DWI - Comparing the utility of fat fraction and apparent diffusion coefficient to distinguish between malignant and acute osteoporotic vertebral fractures. Dixon 或 DWI - 比较脂肪分数和表观扩散系数在鉴别良恶性和急性骨质疏松性椎体骨折中的效用。
Eur J Radiol. 2020 Nov;132:109342. doi: 10.1016/j.ejrad.2020.109342. Epub 2020 Oct 8.
3
Shortening the acquisition time of whole-body MRI: 3D T1 gradient echo Dixon vs fast spin echo for metastatic screening in prostate cancer.
缩短全身 MRI 采集时间:3D T1 梯度回波 Dixon 与快速自旋回波在前列腺癌转移筛查中的比较。
Eur Radiol. 2020 Jun;30(6):3083-3093. doi: 10.1007/s00330-019-06515-y. Epub 2020 Feb 17.
4
Localising occult prostate cancer metastasis with advanced imaging techniques (LOCATE trial): a prospective cohort, observational diagnostic accuracy trial investigating whole-body magnetic resonance imaging in radio-recurrent prostate cancer.运用先进影像技术定位隐匿性前列腺癌转移病灶(LOCATE 试验):一项前瞻性队列、观察性诊断准确性试验,旨在研究全身磁共振成像在放射性复发性前列腺癌中的应用。
BMC Med Imaging. 2019 Nov 15;19(1):90. doi: 10.1186/s12880-019-0380-y.
5
Comparison of proton density fat fraction, simultaneous R2*, and apparent diffusion coefficient for assessment of focal vertebral bone marrow lesions.质子密度脂肪分数、同时 R2*和表观扩散系数在评估局灶性椎体骨髓病变中的比较。
Clin Radiol. 2020 Feb;75(2):123-130. doi: 10.1016/j.crad.2019.09.141. Epub 2019 Oct 31.
6
Multimodality Imaging of Prostate Cancer.前列腺癌的多模态影像学
J Nucl Med. 2019 Oct;60(10):1350-1358. doi: 10.2967/jnumed.119.228320. Epub 2019 Sep 3.
7
Optimising TNM Staging of Patients with Prostate Cancer Using WB-MRI.利用全身磁共振成像(WB-MRI)优化前列腺癌患者的TNM分期
J Belg Soc Radiol. 2016 Nov 19;100(1):101. doi: 10.5334/jbr-btr.1209.
8
Magnetic Resonance Imaging Proton Density Fat Fraction Associates With Progression of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease.磁共振质子密度脂肪分数与非酒精性脂肪性肝病患者纤维化进展相关。
Gastroenterology. 2018 Aug;155(2):307-310.e2. doi: 10.1053/j.gastro.2018.04.014. Epub 2018 Apr 13.
9
Proton density fat fraction (PDFF) MRI for differentiation of benign and malignant vertebral lesions.质子密度脂肪分数(PDFF)MRI 用于鉴别良恶性椎体病变。
Eur Radiol. 2018 Jun;28(6):2397-2405. doi: 10.1007/s00330-017-5241-x. Epub 2018 Jan 8.
10
Lymph node imaging in initial staging of prostate cancer: An overview and update.前列腺癌初始分期中的淋巴结成像:综述与更新
World J Radiol. 2017 Oct 28;9(10):389-399. doi: 10.4329/wjr.v9.i10.389.