Department of Exercise and Health, Institute of Sports Medicine, Paderborn University, Paderborn, Germany; and.
Department of Neurology, Division of Epilepsy and Clinical Neurophysiology, Brigham and Women's Hospital, Boston, Massachusetts.
J Clin Neurophysiol. 2023 Jul 1;40(5):391-397. doi: 10.1097/WNP.0000000000000996. Epub 2023 Mar 15.
Sport-related concussion (SRC) has been defined as a subset of mild traumatic brain injury (mTBI), without structural abnormalities, reflecting a functional disturbance. Over the past decade, SRC has gained increasing awareness and attention, which coincides with an increase in incidence rates. Because this injury has been considered one of the most challenging encounters for clinicians, there is a need for objective biomarkers to aid in diagnosis (i.e., presence/severity) and management (i.e., return to sport) of SRC/mTBI.The primary aim of this article was to present state-of-the-art neurophysiologic methods (e.g., electroencephalography, magnetoencephalography, transcranial magnetic stimulation, and autonomic nervous system) that are appropriate to investigate the complex pathophysiological process of a concussion. A secondary aim was to explore the potential for evidence-based markers to be used in clinical practice for SRC management. The article concludes with a discussion of future directions for SRC research with specific focus on clinical neurophysiology.
运动相关性脑震荡（SRC）已被定义为轻度创伤性脑损伤（mTBI）的一个子集，没有结构异常，反映了功能障碍。在过去的十年中，SRC 越来越受到关注，发病率也有所上升。由于这种损伤被认为是临床医生最具挑战性的情况之一，因此需要客观的生物标志物来辅助 SRC/mTBI 的诊断（即存在/严重程度）和管理（即重返运动）。本文的主要目的是介绍最先进的神经生理学方法（例如，脑电图、脑磁图、经颅磁刺激和自主神经系统），这些方法适合研究脑震荡的复杂病理生理过程。次要目的是探讨基于证据的标志物在 SRC 管理的临床实践中的应用潜力。本文最后讨论了 SRC 研究的未来方向，特别关注临床神经生理学。
