Environmental Sciences Postgraduate Program.
Biomolecular Detection Center.
Gac Med Mex. 2023;159(1):44-48. doi: 10.24875/GMM.M22000735.
Owing to its ability to reduce the toxicity of environmental pollutants that are risk factors for diabetes and obesity, the use of probiotic bacteria might aid the treatment of these diseases.
To determine the effects of chronic exposure to low-dose malathion on weight and glucose levels in mice, as well as to evaluate the protective role of a probiotic supplement.
Weight and serum glucose levels of four groups of mice (control, malathion-exposed [10 ppm], probiotics and malathion + probiotics) were determined every 10 days for 180 days.
Malathion administration induced an increase in weight and glucose levels in the malathion group mice in comparison with the other groups.
Consumption of food contaminated with malathion residues increases glucose levels and favors weight gain, while consumption of probiotics reduces the effects generated by residues in food.
由于益生菌能够降低糖尿病和肥胖等环境污染物的毒性，因此其可能有助于这些疾病的治疗。
确定慢性低剂量马拉硫磷暴露对小鼠体重和血糖水平的影响，并评估益生菌补充剂的保护作用。
180 天内，每隔 10 天测量四组小鼠（对照组、马拉硫磷暴露组[10ppm]、益生菌组和马拉硫磷+益生菌组）的体重和血清葡萄糖水平。
与其他组相比，马拉硫磷组小鼠的体重和血糖水平升高。
食用受马拉硫磷残留污染的食物会增加血糖水平并导致体重增加，而食用益生菌则会降低食物残留产生的影响。
