Effect of probiotics on glucose levels and weight gain in mice exposed to low doses of malathion.

INTRODUCTION

Owing to its ability to reduce the toxicity of environmental pollutants that are risk factors for diabetes and obesity, the use of probiotic bacteria might aid the treatment of these diseases.

OBJECTIVE

To determine the effects of chronic exposure to low-dose malathion on weight and glucose levels in mice, as well as to evaluate the protective role of a probiotic supplement.

METHODS

Weight and serum glucose levels of four groups of mice (control, malathion-exposed [10 ppm], probiotics and malathion + probiotics) were determined every 10 days for 180 days.

RESULTS

Malathion administration induced an increase in weight and glucose levels in the malathion group mice in comparison with the other groups.

CONCLUSIONS

Consumption of food contaminated with malathion residues increases glucose levels and favors weight gain, while consumption of probiotics reduces the effects generated by residues in food.