Department of Pediatrics, Tokai University Hachioji Hospital, Tokyo, Japan; Department of Pediatrics, Tokai University School of Medicine, Kanagawa, Japan.
Department of Basic Clinical Science and Public Health, Tokai University School of Medicine, Kanagawa, Japan.
Allergol Int. 2023 Oct;72(4):545-550. doi: 10.1016/j.alit.2023.03.001. Epub 2023 Mar 17.
In children with asthma, there are many cases in which wheeze is confirmed by auscultation with a normal lung function, or in which the lung function is decreased without wheeze. Using an objective lung sound analysis, we examined the effect of wheeze and the lung function on lung sound parameters in children with asthma.
A total of 114 children with asthma (males to females = 80: 34, median age 10 years old) were analyzed for their lung sound parameters using conventional methods, and wheeze and the lung function were checked. The effects of wheeze and the lung function on lung sound parameters were examined.
The patients with wheeze or decreased forced expiratory flow and volume in 1 s (FEV) (% pred) showed a significantly higher sound power of respiration and expiration-to-inspiration sound power ratio (E/I) than those without wheeze and a normal FEV (% pred). There was no marked difference in the sound power of respiration or E/I between the patients without wheeze and a decreased FEV (% pred) and the patients with wheeze and a normal FEV (% pred).
Our data suggest that bronchial constriction in the asthmatic children with wheeze similarly exists in the asthmatic children with a decreased lung function. A lung sound analysis is likely to enable an accurate understanding of airway conditions.
在哮喘患儿中，存在听诊可闻及哮鸣音但肺功能正常，或哮鸣音缺失但肺功能降低的情况。我们采用客观的肺音分析方法，研究了哮鸣音和肺功能对哮喘患儿肺音参数的影响。
共分析了 114 例哮喘患儿（男/女=80/34，中位年龄 10 岁）的肺音参数，同时检查了哮鸣音和肺功能。考察了哮鸣音和肺功能对肺音参数的影响。
有哮鸣音或 1 秒用力呼气量（FEV）（%预计值）降低的患儿，呼吸音声强和呼气相/吸气相声强比（E/I）显著高于无哮鸣音和 FEV（%预计值）正常的患儿。无哮鸣音但 FEV（%预计值）降低的患儿与有哮鸣音且 FEV（%预计值）正常的患儿之间，呼吸音声强或 E/I 无显著差异。
我们的数据提示，哮喘伴哮鸣音患儿的支气管收缩在哮喘伴肺功能降低患儿中同样存在。肺音分析可能有助于准确了解气道状况。
