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头皮微灌注:一种用于脱发治疗的新型药物递送技术。

Scalp Microinfusion: A Novel Drug Delivery Technique for Hair Loss Treatment.

作者信息

Cortez de Almeida Rita Fernanda, Melo Daniel Fernandes, Tosti Antonella

机构信息

Department of Dermatology, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.

Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida, USA.

出版信息

Skin Appendage Disord. 2023 Mar;9(2):81-83. doi: 10.1159/000528446. Epub 2023 Jan 5.

DOI:10.1159/000528446
PMID:36937154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10015642/
Abstract

Scalp microinfusion is a promising novel drug delivery technique for hair loss treatment. We discuss the MMP® technique and review its possible use in alopecias. MMP® technique provides a small amount of drugs delivered homogeneously into the skin combined with micro-needling and can, therefore, provide optimal delivery. However, literature on this technique is limited to a few case reports despite its wide use in some countries. Further studies are needed to standardize protocols.

摘要

头皮微灌注是一种用于脱发治疗的很有前景的新型药物递送技术。我们讨论了MMP®技术,并综述了其在脱发症中的可能应用。MMP®技术结合微针将少量药物均匀地递送至皮肤中,因此可以实现最佳递送效果。然而,尽管该技术在一些国家广泛使用,但关于它的文献仅限于少数病例报告。需要进一步的研究来规范方案。

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1
Scalp Microinfusion: A Novel Drug Delivery Technique for Hair Loss Treatment.头皮微灌注:一种用于脱发治疗的新型药物递送技术。
Skin Appendage Disord. 2023 Mar;9(2):81-83. doi: 10.1159/000528446. Epub 2023 Jan 5.
2
Comparison of oral minoxidil, finasteride, and dutasteride for treating androgenetic alopecia.比较米诺地尔、非那雄胺和度他雄胺治疗雄激素性脱发。
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3
[Hair loss].[脱发]
Praxis (Bern 1994). 2003 Sep 3;92(36):1488-96. doi: 10.1024/0369-8394.92.36.1488.
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Micro needling: A novel therapeutic approach for androgenetic alopecia, A Review of Literature.微针刺疗法:AGA 的一种新型治疗方法——文献综述
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Transdermal finasteride delivery via powder-carrying microneedles with a diffusion enhancer to treat androgenetic alopecia.经皮递送携粉微针联合扩散增强剂治疗雄激素性脱发。
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Novel drug delivery approaches for the management of hair loss.新型药物递送方法在脱发管理中的应用。
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引用本文的文献

1
Blood pressure changes in patients after Minoxidil microinfusion to treat female pattern alopecia: analysis of a randomized, single blinded, placebo controlled clinical trial.米诺地尔微量输注治疗女性型脱发患者后的血压变化:一项随机、单盲、安慰剂对照临床试验的分析
Arch Dermatol Res. 2025 May 6;317(1):750. doi: 10.1007/s00403-025-04247-2.
2
Male androgenetic alopecia.男性雄激素性脱发
An Bras Dermatol. 2025 Mar-Apr;100(2):308-321. doi: 10.1016/j.abd.2024.08.004. Epub 2025 Jan 13.

本文引用的文献

1
Minimally invasive procedures for the management of female pattern hair loss.女性型脱发的微创处理方法。
J Cosmet Dermatol. 2022 Nov;21(11):5405-5408. doi: 10.1111/jocd.15160. Epub 2022 Jun 25.
2
Successful Treatment of Alopecia Areata Patches with Triamcinolone Acetonide Using MMP®: Report of 2 Cases.使用MMP®曲安奈德成功治疗斑秃斑块:2例报告
Skin Appendage Disord. 2020 Jul;6(4):229-234. doi: 10.1159/000506314. Epub 2020 Jun 18.
3
Use of vibrating anesthetic device reduces the pain of mesotherapy injections: A randomized split-scalp study.使用振动麻醉设备可减轻中胚层疗法注射的疼痛:一项随机半头皮研究。
J Cosmet Dermatol. 2021 Feb;20(2):425-428. doi: 10.1111/jocd.13554. Epub 2020 Jul 8.
4
Novel drug delivery approaches for the management of hair loss.新型药物递送方法在脱发管理中的应用。
Expert Opin Drug Deliv. 2020 Mar;17(3):287-295. doi: 10.1080/17425247.2020.1723543. Epub 2020 Feb 6.
5
How much medication is delivered in a novel drug delivery technique that uses a tattoo machine?新型给药技术采用纹身机给药,其输送的药物剂量是多少?
Int J Dermatol. 2019 Jun;58(6):750-755. doi: 10.1111/ijd.14408. Epub 2019 Mar 3.