Cortez Gabriel Lazzeri, Hassun Karime, Linhares Luciana Ribeiro Patricio, Florenço Verena, Pinheiro Maria Valeria Bussamara, Nascimento Mauricio Mendonça do
Postgraduate Program in Translational Medicine, Department of Medicine, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Department of Dermatology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
An Bras Dermatol. 2025 Mar-Apr;100(2):308-321. doi: 10.1016/j.abd.2024.08.004. Epub 2025 Jan 13.
Male androgenetic alopecia (MAA) is quite common and worsens with age, with a significant impact on quality of life, and is increasingly a reason for consultation with a dermatologist. The etiopathogenesis of MAA is multifactorial and genetic and hormonal influences stand out. MAA starts with the process of follicular miniaturization in diverse phenotypic patterns. The diagnosis of MAA is basically clinical and currently corroborated by well-established trichoscopic findings. Despite this, therapeutic options are limited, especially when one considers medications with a high level of scientific evidence. This review aims to help the general dermatologist towards a better understanding of MAA providing a basis for good individualized and judicious therapeutic decisions.
男性雄激素性脱发（MAA）相当常见，且会随着年龄增长而加重，对生活质量有重大影响，越来越多地成为患者咨询皮肤科医生的原因。MAA的发病机制是多因素的，遗传和激素影响较为突出。MAA始于毛囊在不同表型模式下的微型化过程。MAA的诊断基本上是临床诊断，目前已得到成熟的毛发镜检查结果的证实。尽管如此，治疗选择仍然有限，尤其是当考虑具有高度科学证据的药物时。本综述旨在帮助普通皮肤科医生更好地了解MAA，为做出良好的个体化和明智的治疗决策提供依据。
