Verket Marlo, Jacobsen Malte, Schütt Katharina, Marx Nikolaus, Müller-Wieland Dirk
Department of Medicine I for Cardiology, Angiology and Intensive Care Medicine, University Hospital Aachen, Pauwelsstr. 30, Aachen 52074, Germany.
Eur Heart J Suppl. 2023 Feb 14;25(Suppl A):A36-A41. doi: 10.1093/eurheartjsupp/suac119. eCollection 2023 Feb.
Type 2 diabetes, obesity-related metabolic syndrome, and insulin resistance are the most common metabolic disorders associated with increased cardiovascular risk. In addition, patients with Type 2 diabetes have an increased risk for a more severe course of influenza virus infection, a common pandemic. There is increasing evidence that influenza vaccination in patients with diabetes can safely and effectively reduce all-cause mortality and cardiovascular death. The effects of vaccination appear to be more effective when using higher-dose and quadrivalent vaccines, although subgroup-specific separate analyses in patients with diabetes are lacking. Clinical recommendations address influenza vaccination in all adults with diabetes. From our point of view, it should be an integral part of treatment strategies in patients with diabetes.
2型糖尿病、肥胖相关的代谢综合征和胰岛素抵抗是与心血管风险增加相关的最常见代谢紊乱。此外，2型糖尿病患者感染常见大流行病毒——流感病毒后病情更严重的风险增加。越来越多的证据表明，糖尿病患者接种流感疫苗可安全有效地降低全因死亡率和心血管死亡风险。使用高剂量和四价疫苗时，疫苗接种的效果似乎更显著，不过缺乏针对糖尿病患者亚组的单独分析。临床建议是所有糖尿病成年患者都应接种流感疫苗。在我们看来，它应该成为糖尿病患者治疗策略的一个组成部分。
