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冲突时期的癌症护理:在巴基斯坦治疗来自阿富汗的患者。

Cancer care in times of conflict: Treatment of patients from Afghanistan, in Pakistan.

作者信息

Mahmood Shahid, Khawaja Shehryar Nasir, Yusuf Muhammed Aasim

机构信息

Department of Cancer Registry and Clinical Data Management, Shaukat Khanum Memorial Cancer Hospital and Research Centres, Lahore, Pakistan.

Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centres, Lahore, Pakistan.

出版信息

Front Oncol. 2023 Mar 3;13:1110709. doi: 10.3389/fonc.2023.1110709. eCollection 2023.

Abstract

INTRODUCTION

Afghanistan has been in a near-continuous armed conflict, which has degraded the country's health infrastructure. Due to this, Afghans have opted to seek cancer treatment in Pakistan. This manuscript aims to understand the complex cancer journey of patients from Afghanistan seeking care in the largest tertiary care cancer institutions in Pakistan.

METHODS

This retrospective study explores the demographics, epidemiology and outcomes of Afghan cancer patients treated at the Shaukat Khanum Memorial Cancer Hospital and Research Centres (SKMCH&RC) in Lahore and Peshawar, Pakistan, over the period from 1995 to June 2022.

RESULTS

A total of 6,370 patients from Afghanistan have undergone cancer care since 1995. The mean age at presentation was 40.7 years, 57% were male, and 87% were adults >19 years. Close to 30% of these patients came from Kabul and Nangarhar districts. 56% of all patients presented with stage III or IV disease. 34% of adult patients achieved a complete response to treatment, but more than half of all patients have since been lost to follow-up. Children generally had better outcomes, with 43% showing a complete response to treatment.

DISCUSSION

The cancer journey for these patients remains long and difficult and the inability to ensure follow-up in so many remains frustrating for both patients and providers. The lack of a cancer infrastructure in Afghanistan after decades of conflict, means that policymakers need to develop and support alternative systems and structures to provide post-conflict domestic and cross-border cancer care.

摘要

引言

阿富汗长期处于武装冲突之中,致使该国的医疗卫生基础设施遭到破坏。因此,阿富汗人选择前往巴基斯坦接受癌症治疗。本论文旨在了解在巴基斯坦最大的三级癌症治疗机构就医的阿富汗患者复杂的抗癌历程。

方法

这项回顾性研究探讨了1995年至2022年6月期间,在巴基斯坦拉合尔和白沙瓦的绍卡特·汗姆纪念癌症医院及研究中心(SKMCH&RC)接受治疗的阿富汗癌症患者的人口统计学、流行病学特征及治疗结果。

结果

自1995年以来,共有6370名来自阿富汗的患者接受了癌症治疗。就诊时的平均年龄为40.7岁,57%为男性,87%为19岁以上的成年人。这些患者中近30%来自喀布尔和楠格哈尔地区。所有患者中有56%就诊时已处于III期或IV期疾病。34%的成年患者治疗后获得完全缓解,但此后超过一半的患者失去了随访。儿童的治疗效果通常较好,43%的儿童患者治疗后获得完全缓解。

讨论

这些患者的抗癌历程漫长且艰难,无法确保对如此多患者进行随访,这让患者和医疗服务提供者都感到沮丧。经过数十年冲突后,阿富汗缺乏癌症治疗基础设施,这意味着政策制定者需要建立并支持替代系统和架构,以提供冲突后国内及跨境癌症治疗服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/499f/10020685/446f4516ff54/fonc-13-1110709-g001.jpg

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