Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.
Centre for Epidemiology and Evidence-Based Practice, University of Malaya, Kuala Lumpur, Malaysia.
Nat Med. 2022 Apr;28(4):649-657. doi: 10.1038/s41591-022-01738-x. Epub 2022 Apr 19.
Cancer research currently is heavily skewed toward high-income countries (HICs), with little research conducted in, and relevant to, the problems of low- and middle-income countries (LMICs). This regional discordance in cancer knowledge generation and application needs to be rebalanced. Several gaps in the research enterprise of LMICs need to be addressed to promote regionally relevant research, and radical rethinking is needed to address the burning issues in cancer care in these regions. We identified five top priorities in cancer research in LMICs based on current and projected needs: reducing the burden of patients with advanced disease; improving access and affordability, and outcomes of cancer treatment; value-based care and health economics; quality improvement and implementation research; and leveraging technology to improve cancer control. LMICs have an excellent opportunity to address important questions in cancer research that could impact cancer control globally. Success will require collaboration and commitment from governments, policy makers, funding agencies, health care organizations and leaders, researchers and the public.
癌症研究目前严重偏向高收入国家（HICs），而在中低收入国家（LMICs）进行的相关研究很少。这种癌症知识产生和应用的区域性不协调需要重新平衡。为了促进与区域相关的研究，需要解决中低收入国家研究企业中的几个差距，并且需要对这些地区癌症护理中的热点问题进行彻底的重新思考。我们根据当前和预计的需求，确定了中低收入国家癌症研究的五个优先事项：减轻晚期疾病患者的负担；改善癌症治疗的可及性、可负担性和结果；基于价值的护理和健康经济学；质量改进和实施研究；以及利用技术改善癌症控制。中低收入国家有很好的机会解决可能对全球癌症控制产生影响的癌症研究中的重要问题。成功将需要政府、政策制定者、资助机构、医疗保健组织和领导者、研究人员和公众的合作和承诺。
