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霉酚酸酯引起的伴有皮肤表现的高脂血症。

Mycophenolate mofetil-induced hyperlipidemia with cutaneous manifestations.

作者信息

Yim Rebecca M, Sahni Vikram N, Mathis Jason G

机构信息

Tulane University School of Medicine New Orleans Louisiana USA.

Department of Dermatology University of Utah Salt Lake City Utah USA.

出版信息

Clin Case Rep. 2023 Mar 14;11(3):e7056. doi: 10.1002/ccr3.7056. eCollection 2023 Mar.

DOI:10.1002/ccr3.7056
PMID:36937641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10014514/
Abstract

We report a case of a 49 year old woman who developed biopsy-proven xanthomas on her hands and arms after initiation of Mycophenolate mofetil therapy for systemic lupus erythematosus (SLE) and subsequently went into remission upon cessation of the medication.

摘要

我们报告一例49岁女性，她在开始使用霉酚酸酯治疗系统性红斑狼疮（SLE）后，手部和手臂出现经活检证实的黄瘤，随后在停药后病情缓解。

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Late Transformation of a Dermatofibrosarcoma Protuberans Neck Sarcoma to a Neoplasm With Fibrosarcomatous Elements: Lessons Learned.隆突性皮肤纤维肉瘤颈部肉瘤向具有纤维肉瘤成分的肿瘤的晚期转变：经验教训
Cureus. 2022 Oct 26;14(10):e30690. doi: 10.7759/cureus.30690. eCollection 2022 Oct.
2
Nuclear Receptor PXR in Drug-Induced Hypercholesterolemia.核受体 PXR 在药物性高胆固醇血症中的作用。
Cells. 2022 Jan 18;11(3):313. doi: 10.3390/cells11030313.
3
Xanthomas and atheromas.黄色瘤和粥样瘤。
Atherosclerosis. 2017 Aug;263:315. doi: 10.1016/j.atherosclerosis.2017.06.003. Epub 2017 Jun 6.
4
Screening of a chemical library reveals novel PXR-activating pharmacologic compounds.对一个化学文库进行筛选发现了新型的激活孕烷X受体（PXR）的药理化合物。
Toxicol Lett. 2015 Jan 5;232(1):193-202. doi: 10.1016/j.toxlet.2014.10.009. Epub 2014 Oct 16.
5
Xanthomas: clinical and pathophysiological relations.黄瘤病：临床与病理生理关系
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014 Jun;158(2):181-8. doi: 10.5507/bp.2014.016. Epub 2014 Apr 29.
6
Mechanisms of action of mycophenolate mofetil.霉酚酸酯的作用机制。
Lupus. 2005;14 Suppl 1:s2-8. doi: 10.1191/0961203305lu2109oa.
7
Treatment of hyperlipidemia in cardiac transplant recipients.心脏移植受者高脂血症的治疗
Am Heart J. 2004 Aug;148(2):200-10. doi: 10.1016/j.ahj.2004.03.050.
8
Xanthomas: a marker for hyperlipidemias.黄色瘤：高脂血症的一个标志物。
Bol Asoc Med P R. 2003 Jul-Aug;95(4):12-6.
9
Drug-Induced lipid changes: a review of the unintended effects of some commonly used drugs on serum lipid levels.药物诱导的脂质变化：一些常用药物对血清脂质水平意外影响的综述。
Drug Saf. 2001;24(6):443-56. doi: 10.2165/00002018-200124060-00003.
10
Preliminary risk-benefit assessment of mycophenolate mofetil in transplant rejection.霉酚酸酯在移植排斥反应中的初步风险效益评估。
Drug Saf. 1997 Aug;17(2):75-92. doi: 10.2165/00002018-199717020-00001.