Shaw Peter H, Metts Jonathan, Amankwah Ernest, Eslin Don E, Bradfield Scott, Slayton William B, Hays Brian, Calkins Brian, Rico Juan, Krischer Jeffrey
Pediatrics/Oncology, Children's Wisconsin/Medical College of Wisconsin, Milwaukee, USA.
Pediatric Oncology, Johns Hopkins All Children's Hospital, St. Petersburg, USA.
Cureus. 2023 Feb 16;15(2):e35061. doi: 10.7759/cureus.35061. eCollection 2023 Feb.
Background The Florida Association of Pediatric Tumor Programs (FAPTP) has used the Statewide Patient Information Reporting System (SPIRS) since 1981 to track all new cases of pediatric cancer. We reviewed the last 40 years of data to see how pediatric cancer care has evolved. Methods We retrospectively analyzed SPIRS data from 1981 through 2020 in five-year increments, looking at numbers of new diagnoses, care delivery sites, and trial enrollment in Children's Oncology Group (COG) studies. Results From 1981-2020 Florida's population increased almost 88% while the pediatric population only grew 61%. New pediatric cancer diagnoses increased 326% to over 1,000 new cases/year. The percentage of patients treated at FAPTP centers grew from 30% to 57% with an annual percentage change (APC) of 10.3% (95% Confidence Interval [CI] of 0.6 to 20.9%). The rate of COG clinical trial enrollment decreased from 32% in 1981-1985 to 20% in 2016-2020, for an APC of 8.91% (95% CI of -13.3 to -4.3%). Conclusions The striking increase in pediatric cancer cases in Florida over the last 40 years was out of proportion to the population growth. More patients received care at FAPTP centers, but a lower percentage were enrolled on COG trials.
背景 自1981年以来，佛罗里达儿科肿瘤项目协会（FAPTP）一直使用全州患者信息报告系统（SPIRS）来追踪所有小儿癌症新病例。我们回顾了过去40年的数据，以了解小儿癌症护理的发展情况。方法 我们以五年为增量，回顾性分析了1981年至2020年的SPIRS数据，观察新诊断病例数、护理提供地点以及儿童肿瘤学组（COG）研究中的试验入组情况。结果 1981年至2020年，佛罗里达的人口增长了近88%，而儿科人口仅增长了61%。小儿癌症新诊断病例增加了326%，达到每年1000多例新病例。在FAPTP中心接受治疗的患者比例从30%增长到57%，年百分比变化（APC）为10.3%（95%置信区间[CI]为0.6至20.9%）。COG临床试验入组率从1981 - 1985年的32%下降到2016 - 2020年的20%，APC为8.91%（95% CI为 - 13.3至 - 4.3%）。结论 在过去40年中，佛罗里达小儿癌症病例的显著增加与人口增长不成比例。更多患者在FAPTP中心接受护理，但参加COG试验的患者比例较低。
