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一种易于使用且通用的基于深度学习的睡眠阶段分类器。

An accessible and versatile deep learning-based sleep stage classifier.

作者信息

Hanna Jevri, Flöel Agnes

机构信息

Greifswald University Hospital, Greifswald, Germany.

German Center for Neurodegenerative Diseases, Standort Rostock/Greifswald, Greifswald, Germany.

出版信息

Front Neuroinform. 2023 Mar 2;17:1086634. doi: 10.3389/fninf.2023.1086634. eCollection 2023.

Abstract

Manual sleep scoring for research purposes and for the diagnosis of sleep disorders is labor-intensive and often varies significantly between scorers, which has motivated many attempts to design automatic sleep stage classifiers. With the recent introduction of large, publicly available hand-scored polysomnographic data, and concomitant advances in machine learning methods to solve complex classification problems with supervised learning, the problem has received new attention, and a number of new classifiers that provide excellent accuracy. Most of these however have non-trivial barriers to use. We introduce the Greifswald Sleep Stage Classifier (GSSC), which is free, open source, and can be relatively easily installed and used on any moderately powered computer. In addition, the GSSC has been trained to perform well on a large variety of electrode set-ups, allowing high performance sleep staging with portable systems. The GSSC can also be readily integrated into brain-computer interfaces for real-time inference. These innovations were achieved while simultaneously reaching a level of accuracy equal to, or exceeding, recent state of the art classifiers and human experts, making the GSSC an excellent choice for researchers in need of reliable, automatic sleep staging.

摘要

出于研究目的以及睡眠障碍诊断而进行的人工睡眠评分工作强度大,且评分者之间的评分结果常常存在显著差异,这促使人们多次尝试设计自动睡眠阶段分类器。随着近期大量公开可用的人工标注多导睡眠图数据的引入,以及在机器学习方法方面取得的进展,能够通过监督学习解决复杂的分类问题,该问题受到了新的关注,并且出现了一些具有出色准确率的新型分类器。然而,其中大多数分类器在使用上存在不小的障碍。我们推出了格赖夫斯瓦尔德睡眠阶段分类器(GSSC),它是免费的、开源的,并且可以在任何中等性能的计算机上相对轻松地安装和使用。此外,GSSC经过训练,在各种电极设置上都能表现良好,从而能够通过便携式系统实现高性能的睡眠分期。GSSC还可以很容易地集成到脑机接口中进行实时推理。在实现这些创新的同时,GSSC达到了与近期最先进的分类器和人类专家相当或更高的准确率水平,这使得GSSC成为需要可靠自动睡眠分期的研究人员的绝佳选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcb1/10017438/1e43cf7acf22/fninf-17-1086634-g001.jpg

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