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前列腺癌患者调强放射治疗计划的剂量学验证。

DOSIMETRIC VERIFICATION OF INTENSITY MODULATED RADIOTHERAPY (IMRT) TREATMENT PLANS FOR PROSTATE CANCER PATIENTS.

机构信息

Department of Medical Physics.

University of Applied Health Sciences, Mlinarska 38, Zagreb, Croatia.

出版信息

Acta Clin Croat. 2022 Oct;61(Suppl 3):21-27. doi: 10.20471/acc.2022.61.s3.3.

Abstract

Intensity modulated radiotherapy (IMRT) has become widely used as a standard radiation therapy technique for the treatment of localized prostate cancer. The transition from conformal radiotherapy (3D CRT) to a more complex IMRT technique triggered the need for more thorough verification of the accuracy in the dose delivery. In this work we present the clinical workflow and the results of patient specific quality assurance (PSQA) procedures for 40 prostate cancer patients who have been treated with step and shot IMRT ever since its implementation in our routine clinical practice. PSQA procedures include dosimetric verification of each treatment plan with dedicated rotational phantom and high-resolution matrix detector system Octavius 4D (PTW Freiburg) that allows three-dimensional comparison of the calculated and delivered radiation dose distribution. Our results proved the compliance with the universal tolerance limits recommended for those procedures (1), assuring the safety of the treatment and providing the possibility for the adoption of more stringent constraints in the future.

摘要

调强放疗(IMRT)已广泛应用于局限性前列腺癌的标准放射治疗技术。从适形放疗(3D CRT)向更复杂的调强放疗技术的转变,引发了对剂量输送精度更彻底验证的需求。在这项工作中,我们介绍了自我们的常规临床实践中实施以来,对 40 例接受步进和射击调强放疗的前列腺癌患者的特定于患者的质量保证(PSQA)程序的临床工作流程和结果。PSQA 程序包括使用专用旋转体模和高分辨率矩阵探测器系统 Octavius 4D(PTW Freiburg)对每个治疗计划进行剂量验证,该系统允许对计算和输送的辐射剂量分布进行三维比较。我们的结果证明了符合为这些程序推荐的通用公差限制(1),确保了治疗的安全性,并为将来采用更严格的约束提供了可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dca/10022411/816eae4f6775/acc-61_supp3-21-f1.jpg

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