Department of Otolaryngology-Head & Neck Surgery, The University of Michigan, Ann Arbor, Michigan, USA.
Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan, USA.
Otolaryngol Head Neck Surg. 2023 Jun;168(6):1535-1544. doi: 10.1002/ohn.238. Epub 2023 Jan 29.
Few data are available to guide postadenotonsillectomy (AT) pediatric intensive care (PICU) admission. The aim of this study of children with a preoperative polysomnogram (PSG) was to assess whether preoperative information may predict severe respiratory events (SRE) after AT.
Retrospective cohort study.
Single tertiary center.
Children aged 6 months to 17 years who underwent AT with preoperative polysomnography (2012-2018) were identified by billing codes. Data were extracted from medical records. SRE were defined as any 1 or more of desaturations <80% requiring intervention; newly initiated positive airway pressure; postoperative intubation; pneumonia/pneumonitis; respiratory code, cardiac arrest, or death. We hypothesized that SRE would be associated with age <24 months, major medical comorbidity, obesity (>95th percentile), apnea-hypopnea index (AHI) ≥ 30, and O nadir <70% on PSG. Analysis was performed with multivariable logistic regression.
Of 1774 subjects, 28 (1.7%) experienced SRE. Compared to those without, children with SRE were on average younger (3 vs 5 years, p < .01) with a greater probability of medical comorbidities (59% vs 18%, p < .001). After adjustment for sex, black race, obesity, and age <24 months, children with major medical comorbidity were more likely than other children to have SRE (odds ratio [OR]: 14.2; 95% confidence interval [CI]: [5.7, 35.2]), as were children with AHI ≥ 30 (OR: 7.7 [3.0, 19.9]), or O nadir <70% (OR 6.1 [2.1, 17.9]). Age, obesity, sex, and black race did not independently predict SRE.
PICU admission may be most prudent for children with complex medical co-morbidities, high AHI (>30), and/or low O nadir (<70%).
指导腺样体扁桃体切除术后(AT)入住儿科重症监护病房(PICU)的相关数据十分有限。本研究旨在评估术前多导睡眠图(PSG)是否可预测 AT 后严重呼吸事件(SRE),研究对象为接受术前 PSG 的儿童。
回顾性队列研究。
单中心。
通过计费代码确定 2012 年至 2018 年期间行 AT 术且有术前 PSG 的 6 个月至 17 岁儿童。从病历中提取数据。SRE 定义为任何 1 次或多次血氧饱和度下降至 80%以下需干预、新开始使用气道正压通气、术后插管、肺炎/肺炎、呼吸代码、心脏骤停或死亡。我们假设 SRE 与年龄 <24 个月、重大合并症、肥胖(>95%百分位)、呼吸暂停低通气指数(AHI)≥30 和 PSG 时 O 最低值 <70%有关。采用多变量逻辑回归进行分析。
1774 名患者中 28 名(1.7%)发生 SRE。与无 SRE 组相比,SRE 组患儿年龄更小(3 岁 vs 5 岁,p<0.01),合并症发生率更高(59% vs 18%,p<0.001)。在校正性别、黑人种族、肥胖和年龄 <24 个月后,与其他患儿相比,患有重大合并症的患儿更有可能发生 SRE(比值比[OR]:14.2;95%置信区间[CI]:[5.7,35.2]),AHI≥30 的患儿(OR:7.7[3.0,19.9])和 O 最低值 <70%的患儿(OR:6.1[2.1,17.9])也是如此。年龄、肥胖、性别和黑人种族不能独立预测 SRE。
对于患有复杂合并症、AHI 较高(>30)和/或 O 最低值较低(<70%)的患儿,入住 PICU 可能是最合理的。