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儿童高危阻塞性睡眠呼吸暂停患者腺样体扁桃体切除术后的呼吸并发症。

Postoperative Respiratory Complications After Adenotonsillectomy in Children With High-Risk Obstructive Sleep Apnea.

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Division of Pediatric Otolaryngology-Head and Neck Surgery, Children's Health Medical Center Dallas, Dallas, Texas, USA.

出版信息

Otolaryngol Head Neck Surg. 2024 Dec;171(6):1911-1917. doi: 10.1002/ohn.961. Epub 2024 Aug 28.

Abstract

OBJECTIVE

Identify patient characteristics and polysomnogram (PSG) parameters associated with postoperative respiratory complications after adenotonsillectomy (AT) among children with high-risk obstructive sleep apnea (OSA).

STUDY DESIGN

Case series with chart review.

SETTING

Tertiary care children's hospital.

METHODS

Pediatric patients (<18 years) with high-risk OSA (any 1 of: apnea-hypopnea index [AHI] >30, O nadir <80% and peak CO >60 mm Hg) on overnight PSG from 2019 to 2021 were included. Primary outcomes were major respiratory intervention during the postoperative admission, prolonged hospitalization, and intensive care unit (ICU) stay.

RESULTS

A total of 307 patients met inclusion criteria. Median age was 6.5 years and 63% were male. Twenty-five (8.1%) required major respiratory intervention and 29 (9.7%) required ICU admission after AT. Major interventions and ICU admissions were significantly associated with neuromuscular disease (P < .01), higher obstructive apnea-hypopnea index (oAHI), higher CO peak, and lower O nadir. Prolonged admission had similar findings except oAHI was not significantly associated. Younger children were significant more likely to require ICU admission or prolonged admission.

CONCLUSION

Increased oAHI and worsening O and CO parameters on preoperative PSG were associated with postoperative respiratory complications in children with high-risk OSA. Children with neuromuscular disease and age 0 to 2 had higher risk of ICU stay and prolonged hospitalization. Clinicians should recognize the importance of parameters beyond oAHI when anticipating postoperative monitoring.

摘要

目的

确定与高危阻塞性睡眠呼吸暂停(OSA)儿童腺样体扁桃体切除术后(AT)术后呼吸并发症相关的患者特征和多导睡眠图(PSG)参数。

研究设计

病例系列回顾性研究。

设置

三级保健儿童医院。

方法

纳入 2019 年至 2021 年期间接受过夜间 PSG 检查的患有高危 OSA(任何 1 项:呼吸暂停低通气指数[AHI]>30、O 最低<80%和峰值 CO>60mmHg)的小儿患者(<18 岁)。主要结局为术后住院期间的主要呼吸干预、延长住院时间和重症监护病房(ICU)入住。

结果

共有 307 名患者符合纳入标准。中位年龄为 6.5 岁,63%为男性。25 名(8.1%)需要主要呼吸干预,29 名(9.7%)在 AT 后需要 ICU 入院。主要干预和 ICU 入院与神经肌肉疾病显著相关(P<.01),阻塞性呼吸暂停低通气指数(oAHI)较高、CO 峰值较高、O 最低较低。延长住院时间也有类似的发现,只是 oAHI 没有显著相关。年龄较小的儿童更有可能需要 ICU 入院或延长入院。

结论

术前 PSG 上 oAHI 增加和 O 和 CO 参数恶化与高危 OSA 儿童术后呼吸并发症相关。患有神经肌肉疾病和年龄 0 至 2 岁的儿童 ICU 入住和延长住院的风险更高。临床医生在预测术后监测时应认识到 oAHI 以外的参数的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4e3/11605024/41005dc22786/OHN-171-1911-g001.jpg

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