Department of Child, Family, & Population Health Nursing, University of Washington, Seattle, Washington, USA
Institute of Child Development, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.
BMJ Open. 2023 Mar 20;13(3):e066655. doi: 10.1136/bmjopen-2022-066655.
The purpose of the current study, The National Institute of Child Health and Human Development (NICHD) Study of Health in Early and Adult Life (SHINE), was to build on the landmark Study of Early Child Care and Youth Development (SECCYD), a longitudinal birth cohort initiated in 1991, by conducting a health-focused follow-up of the now adult participants. This effort has produced an invaluable resource for the pursuit of life course research examining links between early life risk and resilience factors and adulthood health and disease risk.
Of the 927 NICHD SECCYD participants available for recruitment in the current study, 705 (76.1%) participated in the study. Participants were between 26 and 31 years and living in diverse geographic locations throughout the USA.
In descriptive analyses, the sample exhibited risk on health status indicators, especially related to obesity, hypertension and diabetes. Of particular concern, the prevalence of hypertension (29.4%) and diabetes (25.8%) exceeded national estimates in similar-age individuals. Health behaviour indicators generally tracked with the parameters of poor health status, showing a pattern of poor diet, low activity and disrupted sleep. The juxtaposition of the sample's relatively young age (mean=28.6 years) and high educational status (55.6% college educated or greater) with its poor health status is noteworthy, suggesting a dissociation between health and factors that are typically health protective. This is consistent with observed population health trends, which show a worsening of cardiometabolic health status in younger generations of Americans.
The current study, SHINE, lays the groundwork for future analyses in which the uniquely robust measures collected as a part of the original NICHD SECCYD will be leveraged to pinpoint specific early life risk and resilience factors as well as the correlates and potential mechanisms accounting for variability in health and disease risk indicators in young adulthood.
本研究,即儿童健康与人类发展研究所(NICHD)的早期与成人生活健康研究(SHINE),旨在在前瞻性儿童早期照料与青年发展研究(SECCYD)的基础上进一步拓展,该研究是一项始于 1991 年的纵向出生队列研究,对现在已成年的参与者进行健康相关的随访。这一努力为生命历程研究提供了宝贵的资源,这些研究考察了早期生活风险和复原力因素与成年期健康和疾病风险之间的联系。
在当前研究中,共有 927 名可招募的 NICHD SECCYD 参与者,其中 705 名(76.1%)参与了该研究。参与者年龄在 26 至 31 岁之间,居住在美国各地不同的地理位置。
在描述性分析中,该样本在健康状况指标上表现出风险,尤其是与肥胖、高血压和糖尿病相关的风险。尤其值得关注的是,高血压(29.4%)和糖尿病(25.8%)的患病率高于相似年龄人群的全国估计值。健康行为指标通常与不良健康状况的参数相吻合,表现为不良的饮食、低活动量和睡眠中断。样本相对较年轻(平均 28.6 岁)且受教育程度较高(55.6%以上受过大学教育)与较差的健康状况之间的反差值得注意,这表明健康状况与通常对健康具有保护作用的因素之间存在脱节。这与观察到的人口健康趋势一致,这些趋势显示美国年轻一代的心血管代谢健康状况正在恶化。
当前的 SHINE 研究为未来的分析奠定了基础,这些分析将利用原始 NICHD SECCYD 中收集的独特强大措施,确定特定的早期生活风险和复原力因素,以及解释年轻人健康和疾病风险指标变异性的相关性和潜在机制。