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诊断难题:我们对坏死性涎腺化生的经验

Diagnostic dilemma: our experience with necrotising sialometaplasia.

作者信息

Mohanraj Lekhaa, Singh Urvashi, Lakshmanan Somu

机构信息

Otorhinolaryngology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.

Otorhinolaryngology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India

出版信息

BMJ Case Rep. 2023 Mar 21;16(3):e252481. doi: 10.1136/bcr-2022-252481.

Abstract

A man in his 40s presented to our outpatient department with a painful ulcer in the oral cavity for 1 week. After intraoral examination, a single hard palate ulcer, which was non-tender on palpation, was noted. Baseline blood investigations such as haemogram and serological evaluation were within normal limits. Under local anaesthesia, an excisional biopsy was performed. The histopathological examination revealed a reactive necrotising inflammatory process involving minor salivary glands with no cytological atypia. Weekly follow-up was performed and at the end of 4 weeks, complete healing of the lesion had occurred without any further intervention.

摘要

一名40多岁男性因口腔疼痛性溃疡1周前来我院门诊就诊。口腔检查发现硬腭有单个溃疡,触诊时无压痛。血常规和血清学评估等基线血液检查结果均在正常范围内。在局部麻醉下进行了切除活检。组织病理学检查显示为累及小唾液腺的反应性坏死性炎症过程,无细胞学异型性。每周进行随访,4周结束时,病变完全愈合,无需进一步干预。

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本文引用的文献

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J Dent Sci. 2020 Sep;15(3):390-392. doi: 10.1016/j.jds.2020.03.001. Epub 2020 Mar 25.
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BMJ Case Rep. 2016 Oct 27;2016:bcr2015211348. doi: 10.1136/bcr-2015-211348.
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Necrotizing sialometaplasia: A diagnostic dilemma!坏死性涎腺化生:一种诊断难题!
J Oral Maxillofac Pathol. 2014 Sep-Dec;18(3):420-2. doi: 10.4103/0973-029X.151336.
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The clinical, histologic, and treatment spectrum in necrotizing sialometaplasia.坏死性涎腺化生的临床、组织学和治疗谱。
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