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胸腔镜与开胸肺叶切除术治疗先天性肺畸形的短期疗效比较。

Short-term outcomes of thoracoscopic versus open lobectomy for congenital lung malformations.

机构信息

Division of Pediatric Surgery, Department of Surgery, Loma Linda University School of Medicine, 11175 Campus St, Suite 21111, Loma Linda, CA, USA.

Division of Plastic Surgery, Department of Surgery, Kaiser Permanente, San Jose, CA, USA.

出版信息

Pediatr Surg Int. 2023 Mar 22;39(1):155. doi: 10.1007/s00383-023-05445-7.

Abstract

PURPOSE

Thoracoscopic and open approaches for the management of congenital lung malformations (CLM) has been debated. The aim of this study is to compare 30-day outcomes for non-emergent lobectomies in children.

METHODS

The National Surgical Quality Improvement Program-Pediatric database was queried for patients undergoing CLM resection from 2013 to 2020. Outcomes were compared by operative technique in an intention-to-treat model and then propensity matched.

RESULTS

2157 patients met inclusion criteria and underwent non-emergent pulmonary lobectomy for CLM. The intended operative approach was thoracoscopic in 57.7% of patients. Patients in the open group compared to the thoracoscopic were more likely to be born premature, have chronic lung disease, require preoperative oxygen support, and be ventilator dependent. After propensity matching, there was no statistically significant difference in 30-day mortality, unplanned readmission, and other complications between the thoracoscopic and open groups. Thoracoscopic approach was associated with a shorter length of stay. The proportion of cases approached via thoracoscopy increased over time from 48.8% in 2013 to 69.9% in 2020.

CONCLUSIONS

This large multicenter retrospective matched analysis demonstrates thoracoscopic lobectomy in children has similar favorable 30-day outcomes and shorter length of stay for the non-emergent management of CLM, compared to open thoracotomy.

LEVEL OF EVIDENCE

Level III.

摘要

目的

对于先天性肺畸形(CLM)的治疗,胸腔镜和开放性方法一直存在争议。本研究旨在比较儿童非紧急肺叶切除术的 30 天结局。

方法

从 2013 年到 2020 年,国家手术质量改进计划-儿科数据库被查询用于接受 CLM 切除的患者。在意向治疗模型中通过手术技术比较结果,然后进行倾向匹配。

结果

2157 例患者符合纳入标准,并接受非紧急肺叶切除术治疗 CLM。胸腔镜手术的预期手术方法占 57.7%。与胸腔镜组相比,开放性组的患者更有可能早产、患有慢性肺部疾病、需要术前吸氧支持和依赖呼吸机。在倾向匹配后,胸腔镜组和开放性组在 30 天死亡率、非计划性再入院和其他并发症方面无统计学显著差异。胸腔镜方法与较短的住院时间相关。胸腔镜手术的比例从 2013 年的 48.8%增加到 2020 年的 69.9%。

结论

这项大型多中心回顾性匹配分析表明,与开放性开胸术相比,胸腔镜肺叶切除术在儿童中用于非紧急 CLM 的管理具有相似的 30 天良好结局和较短的住院时间。

证据水平

III 级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95a5/10030530/ad87c094440a/383_2023_5445_Fig1_HTML.jpg

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