Patil Vaibhav, Hedau Madhuri, Kaore Megha, Badar Shweta, Kadam Mukund, Chaudhari Sandeep, Rawool Deepak, Barbuddhe Sukhadeo, Vergis Jess, Kurkure Nitin
Department of Veterinary Pathology, Nagpur Veterinary College, Maharashtra Animal and Fishery Sciences University, Seminary Hills, Nagpur, 440006, Maharashtra, India.
Department of Poultry Sciences, Nagpur Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, 440006, Maharashtra, India.
Trop Anim Health Prod. 2023 Mar 21;55(2):126. doi: 10.1007/s11250-023-03543-1.
Fowl typhoid (FT) is an economically significant bacterial disease of layers leading to a drastic drop in egg production. Due to increased public health concerns about antibiotics in poultry feed, a search for new safe antimicrobials for treating fowl typhoid is crucial. The antimicrobial effect of cinnamaldehyde essential oil (CnEO) against fowl typhoid in layers was investigated in this experiment. The 60-week-old BV300-layer birds (n = 100) were divided into five groups: the non-challenged control group A, only cinnamaldehyde-treated group B (CnEO @ 1:8000 dilutions through drinking water for 60 days), the challenged group C, challenged plus cinnamaldehyde therapy group D (CnEO @ 1:8000 dilutions through drinking water from 16 to 30 dpi), and challenged plus antibiotic therapy group E (chloramphenicol @ 1 gm/5lit through drinking water from 16 to 30 dpi). Hens from all challenged groups were challenged with Salmonella Gallinarum (VTCCBAA588) @ 1 × 10 CFU/ml orally. Various parameters such as clinical signs, mortality, egg production and egg weight, colony-forming unit (CFU) count of cecal content, eggshell surface, and egg yolk were evaluated all through 60 days of an experimental trial. Results indicated that, in the case of the cinnamaldehyde therapeutic group, there was a significant improvement in egg production, mild clinical signs, lower feed conversion ratio (FCR), and a significantly lower bacterial count in ceca and on the eggshell surface compared to the control challenge group. Thus, CnEO @ 1:8000 dilutions through drinking water can be a potential antimicrobial for controlling fowl typhoid.
禽伤寒（FT）是蛋鸡一种具有经济重要性的细菌性疾病，会导致产蛋量急剧下降。由于公众对家禽饲料中抗生素的健康问题日益关注，寻找治疗禽伤寒的新型安全抗菌药物至关重要。本实验研究了肉桂醛精油（CnEO）对蛋鸡禽伤寒的抗菌效果。将60周龄的BV300蛋鸡（n = 100）分为五组：未受挑战的对照组A、仅用肉桂醛处理的组B（通过饮水给予1:8000稀释的CnEO，持续60天）、受挑战组C、受挑战加肉桂醛治疗组D（从攻毒后第16天至30天通过饮水给予1:8000稀释的CnEO）、受挑战加抗生素治疗组E（从攻毒后第16天至30天通过饮水给予每5升含1克氯霉素）。所有受挑战组的母鸡经口用1×10⁸CFU/ml鸡伤寒沙门氏菌（VTCC BAA588）进行攻毒。在为期60天的实验期间，评估了各种参数，如临床症状、死亡率、产蛋量和蛋重、盲肠内容物、蛋壳表面和蛋黄的菌落形成单位（CFU）计数。结果表明，在肉桂醛治疗组中，与对照攻毒组相比，产蛋量有显著改善，临床症状较轻，饲料转化率（FCR）较低，盲肠和蛋壳表面的细菌计数显著降低。因此，通过饮水给予1:8000稀释的CnEO可能是控制禽伤寒的一种潜在抗菌药物。
