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促甲状腺素抑制疗法用于治疗伴有巨大复发性颈部淋巴结的乳头状甲状腺癌。

Thyrotropin suppression therapy for papillary thyroid carcinoma with a huge recurred neck lymph node.

作者信息

Choi Jung Bum, Kim Dong-Il, Paik Hyun-June, Lee Seung Joo, Jung Chang Shin, Kang Seok Kyung, Jung Youn Joo, Kim Hyun Yul

机构信息

Department of Surgery, Pusan National University Hospital, Busan, Korea.

Department of Surgery, Pusan National University Yangsan Hospital, Yangsan, Korea.

出版信息

Korean J Clin Oncol. 2020 Dec;16(2):145-147. doi: 10.14216/kjco.20023. Epub 2020 Dec 31.

DOI:10.14216/kjco.20023
PMID:36945712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9942732/
Abstract

Differentiated thyroid cancer (DTC) originating from thyroid tissue is affected by thyrotropin (TSH). TSH suppression therapy is usually recommended after thyroidectomy in cases of DTC. A 57-year-old woman who harbored a very huge recurred lymph node underwent TSH suppression therapy because of the risk of surgical complications. After TSH suppression, the huge neck lymph node exhibited a response and decreased in size. She had been followed up for 144 months. TSH suppression therapy could be considered as an alternative treatment option in a recurred DTC patient with a high perioperative risk.

摘要

起源于甲状腺组织的分化型甲状腺癌(DTC)受促甲状腺激素(TSH)影响。对于DTC患者,通常建议在甲状腺切除术后进行TSH抑制治疗。一名57岁女性因存在手术并发症风险,对其复发的巨大淋巴结进行了TSH抑制治疗。TSH抑制治疗后,颈部巨大淋巴结出现反应并缩小。对她进行了144个月的随访。对于围手术期风险高的复发性DTC患者,TSH抑制治疗可被视为一种替代治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4857/9942732/deeadb0dc4cc/kjco-16-2-145f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4857/9942732/275d11f078ef/kjco-16-2-145f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4857/9942732/007e4acee75e/kjco-16-2-145f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4857/9942732/deeadb0dc4cc/kjco-16-2-145f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4857/9942732/275d11f078ef/kjco-16-2-145f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4857/9942732/007e4acee75e/kjco-16-2-145f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4857/9942732/deeadb0dc4cc/kjco-16-2-145f3.jpg

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Levothyroxine suppression of thyroglobulin in patients with differentiated thyroid carcinoma.左甲状腺素对分化型甲状腺癌患者甲状腺球蛋白的抑制作用
J Clin Endocrinol Metab. 1999 Dec;84(12):4549-53. doi: 10.1210/jcem.84.12.6190.
8
Treatment of benign nodular thyroid disease.良性结节性甲状腺疾病的治疗。
N Engl J Med. 1998 May 14;338(20):1438-47. doi: 10.1056/NEJM199805143382007.