College of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225009, Jiangsu Province, China.
Joint International Research Laboratory of Agricultural & Agri-Product Safety, Yangzhou University, Yangzhou 225009, Jiangsu Province, China.
J Insect Sci. 2023 Mar 1;23(2). doi: 10.1093/jisesa/iead013.
American foulbrood (AFB) is a cosmopolitan bacterial disease that affects honey bee (Apis mellifera) larvae and causes great economic losses in apiculture. Currently, no satisfactory methods are available for AFB treatment mainly due to the difficulties to eradicate the tenacious spores produced by the etiological agent of AFB, Paenibacillus larvae (Bacillales, Paenibacillaceae). This present review focused on the beneficial bacteria that displayed antagonistic activities against P. larvae and demonstrated potential in AFB control. Emphases were placed on commensal bacteria (genus Bacillus and lactic acid bacteria in particular) in the alimentary tract of honey bees. The probiotic roles lactic acid bacteria play in combating the pathogenic P. larvae and the limitations referring to the application of these beneficial bacteria were addressed.
美洲幼虫腐臭病（AFB）是一种世界性的细菌性疾病，影响蜜蜂（Apis mellifera）幼虫，并在养蜂业造成巨大的经济损失。目前，由于难以根除 AFB 的病原物，蜡状芽孢杆菌（Bacillales，蜡状芽孢杆菌科）产生的顽强孢子，尚无令人满意的 AFB 治疗方法。本综述重点介绍了对蜡状芽孢杆菌表现出拮抗活性并具有 AFB 控制潜力的有益细菌。重点放在蜜蜂消化道中的共生细菌（属芽孢杆菌和乳酸菌特别是）上。讨论了乳酸菌在对抗病原性蜡状芽孢杆菌中的益生菌作用以及应用这些有益细菌的局限性。
