Department of Orthopaedic Surgery, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark.
Department of General Practice, Amsterdam UMC Location, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
J Bone Joint Surg Am. 2023 May 17;105(10):797-804. doi: 10.2106/JBJS.22.01293. Epub 2023 Mar 22.
Patient-reported outcome measures such as the Oxford Hip Score (OHS) can capture patient-centered perspectives on outcomes after total hip arthroplasty (THA). The OHS assesses hip pain and functional limitations, but defining interpretation threshold values for the OHS is warranted so that numerical OHS values can be translated into whether patients have experienced clinically meaningful changes. Therefore, we determined the minimal important change (MIC), patient acceptable symptom state (PASS), and treatment failure (TF) threshold values for the OHS at 12 and 24-month follow-up in patients undergoing THA.
This cohort study used data from patients undergoing THA at 1 public hospital between July 2016 and April 2021. At 12 and 24 months postoperatively, patients provided responses for the OHS and for 3 anchor questions about whether they had experienced changes in hip pain and function, whether they considered their symptom state to be satisfactory, and if it was not satisfactory, whether they considered the treatment to have failed. The anchor-based adjusted predictive modeling method was used to determine interpretation threshold values. Baseline dependency was evaluated using a new item-split method. Nonparametric bootstrapping was used to determine 95% confidence intervals (CIs).
Complete data were obtained for 706 (69%) of 1,027 and 728 (66%) of 1,101 patients at 12 and 24 months postoperatively, respectively. These patients had a median age of 70 years, and 55% to 56% were female. Adjusted OHS MIC values were 6.3 (CI, 4.6 to 8.1) and 5.2 (CI, 3.6 to 6.7), adjusted OHS PASS values were 30.6 (CI, 29.0 to 32.2) and 30.5 (CI, 29.3 to 31.8), and adjusted OHS TF values were 25.5 (CI, 22.9 to 27.7) and 27.0 (CI, 25.2 to 28.8) at 12 and 24 months postoperatively, respectively. MIC values were 5.4 (CI, 2.1 to 9.1) and 5.0 (CI, 1.9 to 8.7) higher at 12 and 24 months, respectively, in patients with a more severe preoperative state.
The established interpretation threshold values advance the interpretation and clinical use of the OHS, and may prove especially beneficial for registry-based evaluations of treatment quality.
Prognostic Level IV . See Instructions for Authors for a complete description of levels of evidence.
患者报告的结果测量,如牛津髋关节评分(OHS),可以从患者的角度评估全髋关节置换术(THA)后的结果。OHS 评估髋关节疼痛和功能受限,但需要确定 OHS 的解释阈值,以便将 OHS 的数值转换为患者是否经历了有临床意义的变化。因此,我们确定了在接受 THA 的患者术后 12 个月和 24 个月随访时 OHS 的最小重要变化(MIC)、可接受症状状态(PASS)和治疗失败(TF)阈值。
这项队列研究使用了 2016 年 7 月至 2021 年 4 月期间在一家公立医院接受 THA 的患者的数据。术后 12 个月和 24 个月,患者对 OHS 以及 3 个锚定问题进行了回答,这些问题是关于他们的髋关节疼痛和功能是否有变化、他们是否认为自己的症状状态是满意的、如果不满意,他们是否认为治疗失败了。使用基于锚定的调整预测建模方法来确定解释阈值。使用新的项目拆分方法评估基线依赖性。使用非参数自举确定 95%置信区间(CI)。
分别有 706 名(69%)和 728 名(66%)接受 THA 的患者在术后 12 个月和 24 个月时获得了完整的数据。这些患者的中位年龄为 70 岁,55%至 56%为女性。调整后的 OHS MIC 值分别为 6.3(CI,4.6 至 8.1)和 5.2(CI,3.6 至 6.7),调整后的 OHS PASS 值分别为 30.6(CI,29.0 至 32.2)和 30.5(CI,29.3 至 31.8),调整后的 OHS TF 值分别为 25.5(CI,22.9 至 27.7)和 27.0(CI,25.2 至 28.8)。在术后 12 个月和 24 个月时,术前状态更严重的患者的 MIC 值分别高出 5.4(CI,2.1 至 9.1)和 5.0(CI,1.9 至 8.7)。
所建立的解释阈值推进了 OHS 的解释和临床应用,对于基于登记的治疗质量评估可能特别有益。
预后 IV 级。请参阅作者说明,以获取证据水平的完整描述。