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中国员工对 SARS-CoV-2 疫苗的接种率和对 SARS-CoV-2 变异疫苗的接种意愿。

The coverage of SARS-CoV-2 vaccination and the willingness to receive the SARS-CoV-2 variant vaccine among employees in China.

机构信息

Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.

Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

出版信息

BMC Public Health. 2023 Mar 22;23(1):542. doi: 10.1186/s12889-023-15294-7.

Abstract

BACKGROUND

COVID-19, which is caused by SARS-CoV-2, is a major global health threat. The dominant variant of SARS-CoV-2 has changed over time due to continuous evolution. We aimed to evaluate the coverage of SARS-CoV-2 vaccination among employees in China, explore their willingness to receive the SARS-CoV-2 variant vaccine and examine the potential factors influencing vaccination coverage and willingness.

METHODS

A cross-sectional epidemiological survey was conducted online from January 1, 2022, to January 30, 2022. The information collected in the survey included sociodemographic characteristics, lifestyle habits, vaccination coverage, willingness to be vaccinated against SARS-CoV-2 variants and the reasons for vaccination and willingness. Multivariable logistic regression models were used to assess the associations of potential factors with the rate of vaccination and the willingness to be vaccinated.

RESULTS

Among 62,395 eligible participants, the coverage of SARS-CoV-2 vaccination was 98.9% for at least one dose and 70.1% for a booster. The great majority of vaccinated individuals (94.4%) voluntarily received the vaccine. A total of 60,694 respondents (97.7%) were willing to be vaccinated against SARS-CoV-2 variants, mainly due to confidence in the effectiveness of vaccines (92.8%). A total of 1431 respondents were unwilling to be vaccinated, mainly because of concerns about the adverse effects of vaccines (77.6%). Longer education duration was associated with a higher rate of SARS-CoV-2 vaccination and willingness to be vaccinated. General or poor health status and having no history of influenza vaccination were associated with a lower rate of SARS-CoV-2 vaccination and willingness to be vaccinated. Additionally, we observed a significant positive association of abuse experience with the willingness to be vaccinated.

CONCLUSION

Although the rate of SARS-CoV-2 vaccination and the willingness to be vaccinated were relatively high in the study population, there were still some respondents with vaccine hesitancy. Relevant strategies based on significant related factors should be developed and implemented to encourage vaccination.

摘要

背景

由 SARS-CoV-2 引起的 COVID-19 是一项重大的全球健康威胁。由于不断进化,SARS-CoV-2 的优势变体随着时间的推移而发生变化。我们旨在评估中国员工中 SARS-CoV-2 疫苗接种的覆盖率,探讨他们对 SARS-CoV-2 变体疫苗的接种意愿,并研究潜在因素对疫苗接种覆盖率和接种意愿的影响。

方法

2022 年 1 月 1 日至 1 月 30 日进行了一项在线横断面流行病学调查。调查收集的信息包括社会人口学特征、生活方式习惯、疫苗接种覆盖率、对 SARS-CoV-2 变体的接种意愿以及接种和意愿的原因。使用多变量逻辑回归模型评估潜在因素与接种率和接种意愿的关联。

结果

在 62395 名合格参与者中,至少接种一剂 SARS-CoV-2 疫苗的覆盖率为 98.9%,接种加强针的覆盖率为 70.1%。绝大多数接种者(94.4%)自愿接种疫苗。共有 60694 名(97.7%)受访者愿意接种 SARS-CoV-2 变体疫苗,主要是因为对疫苗有效性有信心(92.8%)。共有 1431 名受访者不愿意接种疫苗,主要是因为担心疫苗的不良反应(77.6%)。受教育时间较长与 SARS-CoV-2 疫苗接种率和接种意愿较高有关。一般或较差的健康状况以及没有流感疫苗接种史与 SARS-CoV-2 疫苗接种率和接种意愿较低有关。此外,我们观察到滥用经历与接种意愿呈显著正相关。

结论

尽管研究人群中 SARS-CoV-2 疫苗接种率和接种意愿相对较高,但仍有一些受访者对疫苗犹豫不决。应根据相关重要因素制定和实施相关策略,鼓励接种疫苗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5073/10032013/8e34acb96b32/12889_2023_15294_Fig1_HTML.jpg

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