Imran Mohammad, Singh Abhishek, Bhardwaj Anu, Agrawal Deepika
Department of Pharmacology, Maharaja Jitendra Narayan Medical College and Hospital, Cooch Behar, West Bengal, India.
Department of Community Medicine, SHKM Government Medical College, Mewat, Haryana, India.
J Midlife Health. 2022 Jul-Sep;13(3):206-212. doi: 10.4103/jmh.jmh_114_22. Epub 2023 Jan 14.
Prevalence statistics of postmenopausal osteoporosis and knowledge regarding its independent predictors are lacking, especially in India, where every third woman and every eighth man is suffering from it.
This study aims to investigate the prevalence of osteoporosis and associated risk factors among postmenopausal women.
This was a hospital-based prospective cross-sectional study.
This study was carried out among postmenopausal women, who attended orthopaedics outpatient department from August 2020 to July 2021 and 587 women ranging in age between 50 and 80 years who had confirmed menopause were enrolled for the study. Finally, 539 women were recommended for bone mineral density testing, using dual energy X-ray absorptiometry.
To analyze the differences between the groups, a Chi-square and Student's -test were used for the categorical and continuous variables, respectively. < 0.05 was considered to show significant associations.
In our study, 54.7% of subjects belonged to <60 years of age group. Half of the subjects (51.9%) were illiterate. 37.7% of subjects were having 6 or more children. 14.5% of subjects were currently smoking or chewing tobacco. Age of menopause among 38.0% of subjects was after 50 years of age and duration of menopause at the time of enrolment in the study was more than 10 years in 48.8% of subjects. The prevalence of osteoporosis increased with the increase in the parity and increased number of abortions. Subjects with family history of symptoms related to osteoporosis, and fragility fracture; and self-history of fragility fracture had higher prevalence of osteoporosis ( < 0.05).
In our study, the overall prevalence of osteoporotic fractures among postmenopausal females was 82.2% (osteoporosis: 37.5% and osteopenia: 44.7%). The findings of current study and previous studies clearly indicate the urgent need of collective efforts towards the growing problem of osteoporosis in postmenopausal women.
绝经后骨质疏松症的患病率统计数据以及关于其独立预测因素的知识较为缺乏，尤其是在印度，每三名女性和每八名男性中就有一人患有此病。
本研究旨在调查绝经后女性骨质疏松症的患病率及相关危险因素。
这是一项基于医院的前瞻性横断面研究。
本研究针对2020年8月至2021年7月期间到骨科门诊就诊的绝经后女性开展，纳入了587名年龄在50至80岁之间且已确诊绝经的女性参与研究。最后，推荐539名女性采用双能X线吸收法进行骨密度检测。
为分析组间差异，分类变量和连续变量分别采用卡方检验和学生t检验。P<0.05被认为具有显著相关性。
在我们的研究中，54.7%的受试者年龄在60岁以下。一半的受试者（51.9%）为文盲。37.7%的受试者育有6个或更多子女。14.5%的受试者目前吸烟或嚼烟草。38.0%的受试者绝经年龄在50岁之后，48.8%的受试者在研究入组时绝经时间超过10年。骨质疏松症的患病率随着产次和流产次数的增加而升高。有骨质疏松症相关症状家族史和脆性骨折家族史的受试者，以及有脆性骨折个人史的受试者，骨质疏松症患病率更高（P<0.05）。
在我们的研究中，绝经后女性骨质疏松性骨折的总体患病率为82.2%（骨质疏松症：37.5%，骨量减少：44.7%）。本研究及以往研究结果清楚地表明，迫切需要共同努力应对绝经后女性中日益严重的骨质疏松问题。
