Alves Eloize Silva, Ferreira Cintia Stefhany Ripke, Souza Paulo Ricardo, Bruni Andressa Rafaella Silva, Castro Matheus Campos, Saqueti Bruno Henrique Figueiredo, Santos Oscar Oliveira, Madrona Grasiele Scaramal, Visentainer Jesui Vergilio
Post-Graduation Program in Food Science, State University of Maringá, Maringá, PR 87020-900, Brazil.
Chemistry Department, State University of Maringá, Maringá, PR 87020-900, Brazil.
Int J Biol Macromol. 2023 May 31;238:124100. doi: 10.1016/j.ijbiomac.2023.124100. Epub 2023 Mar 21.
Human milk (HM) is essential for newborns' food, but its low storage stability is a limiting factor so that microencapsulation may stabilize and protect compounds sensitive to degradation. This study investigated the action of maltodextrin and gum arabic on freeze-dried HM concerning its quality and solubility. Microencapsulation was evidenced by morphology, and all samples presented high encapsulation efficiency (>85 %), proving to be an efficient process. Furthermore, specific signals in the Fourier-Transform Infrared (FTIR) spectra indicate the interactions between the coating materials and the HM matrix. Gum arabic improved the reconstitution properties of freeze-dried HM (higher solubility, 3 % on average, and lower dissolution time, around 80 %), elucidating its high stabilization capacity, even at low concentrations (5 and 10 %). Despite the best results reached by gum arabic, the addition of maltodextrin proved effective; in other words, its low stabilization capacity enables combinations with gum arabic. A lower polidispersibility (difference of 20 % between samples: control and containing gum arabic) was also observed, which means that the encapsulated samples were more homogeneous. Therefore, through the analysis performed, we recommend using gum arabic alone or with maltodextrin to obtain HM microcapsules with a good quality of reconstitution.
母乳对新生儿来说至关重要,但它储存稳定性差是一个限制因素,因此微囊化可以稳定并保护易降解的化合物。本研究探讨了麦芽糊精和阿拉伯胶对冻干母乳质量和溶解性的影响。通过形态学证明了微囊化的存在,所有样品均呈现出高包封率(>85%),证明这是一个有效的过程。此外,傅里叶变换红外光谱(FTIR)中的特定信号表明了包衣材料与母乳基质之间的相互作用。阿拉伯胶改善了冻干母乳的复溶特性(平均溶解度更高,为3%,溶解时间更短,约为80%),阐明了其即使在低浓度(5%和10%)下也具有很高的稳定能力。尽管阿拉伯胶取得了最佳效果,但麦芽糊精的添加也被证明是有效的;也就是说,其较低的稳定能力使其能够与阿拉伯胶结合使用。还观察到较低的多分散性(对照样品和含阿拉伯胶样品之间相差20%),这意味着包囊化样品更加均匀。因此,通过所进行的分析,我们建议单独使用阿拉伯胶或与麦芽糊精一起使用,以获得具有良好复溶质量的母乳微胶囊。