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采用快速阈值算法(SITA-Faster)进行视野检查的预加载可在最小时间成本的情况下提高视野检查的频率和可靠性。

Frontloading SITA-Faster Can Increase Frequency and Reliability of Visual Field Testing at Minimal Time Cost.

作者信息

Tan Jeremy C K, Kalloniatis Michael, Phu Jack

机构信息

Faculty of Medicine and Health, University of New South Wales, Kensington, NSW, Australia; Department of Ophthalmology, Prince of Wales Hospital, Randwick, NSW, Australia.

School of Optometry and Vision Science, University of New South Wales, Kensington, NSW, Australia; School of Medicine (Optometry), Deakin University, Waurn Ponds, Victoria, Australia.

出版信息

Ophthalmol Glaucoma. 2023 Sep-Oct;6(5):445-456. doi: 10.1016/j.ogla.2023.03.006. Epub 2023 Mar 21.

DOI:10.1016/j.ogla.2023.03.006
PMID:36958625
Abstract

PURPOSE

To report the outcomes of frontloaded visual field (VF) testing (2 tests per eye on the same visit) over 2 longitudinal, consecutive visits using SITA-Faster (SFR) in terms of global indices, reliability metrics, and test duration.

DESIGN

Prospective longitudinal study.

SUBJECTS

A total of 902 eyes of 463 subjects with normal, suspect, or manifest glaucoma.

METHODS

Two intravisit SFR VF tests (T1 and T2) per eye at an initial (T) and follow-up (T) visit.

MAIN OUTCOME MEASURES

Intra- and intervisit global indices, reliability metrics, and test durations.

RESULTS

The mean age of the subjects was 63.6 years, and 58.3% were male. Seven hundred ninety eyes (87.4%) had a diagnosis of glaucoma or glaucoma suspicion. The mean duration between visits was 265.0 (standard deviation 98.8) days. In total, 3608 VF tests were analyzed, with the correlation of mean deviation (MD) values of the frontloaded tests at each visit high (T1/T2 MD correlation at initial visit r = 0.83, root mean squared error [RMSE] = 1.26, follow-up visit r = 0.83, RMSE = 1.25, P < 0.0001) and greater than the correlation of MD between visits (T1/T1 MD correlation r = 0.72, RMSE = 1.31). There was a significant intra-visit decrease in rates of abnormally high sensitivity in the glaucoma hemifield test (3.2% vs. 1.6%, P = 0.0023) and rates of unreliable test results (15.4% vs. 9.2%, P = 0.002) from T1 to T2 in both visits, with a corresponding significant decrease in MD (-1.28 dB vs. -1.68 dB, P < 0.0001) and VF index (P = 0.03). The mean duration of each SFR test was 132.6 (SD 27.2) seconds.

CONCLUSIONS

Frontloading VFs using SFR produced sets of repeatable perimetric data with significant improvement of reliability indices from the first to second test. This may help increase testing frequency at minimal time cost to meet recommended guidelines and for evaluating patients prone to high variability.

FINANCIAL DISCLOSURE(S): The author(s) have no proprietary or commercial interest in any materials discussed in this article.

摘要

目的

报告使用SITA-Faster(SFR)在前瞻性纵向研究中连续两次随访时进行的前置视野(VF)测试(每次就诊时每只眼睛进行2次测试)的结果,包括总体指标、可靠性指标和测试时长。

设计

前瞻性纵向研究。

研究对象

463名患有正常、可疑或明显青光眼的受试者共902只眼睛。

方法

在初次(T)和随访(T)就诊时,每只眼睛进行两次就诊内SFR VF测试(T1和T2)。

主要观察指标

就诊内和就诊间的总体指标、可靠性指标和测试时长。

结果

受试者的平均年龄为63.6岁,58.3%为男性。790只眼睛(87.4%)被诊断为青光眼或疑似青光眼。两次就诊之间的平均时长为265.0(标准差98.8)天。总共分析了3608次VF测试,每次就诊时前置测试的平均偏差(MD)值相关性较高(初次就诊时T1/T2 MD相关性r = 0.83,均方根误差[RMSE]=1.26,随访就诊时r = 0.83,RMSE = 1.25,P<0.0001),且大于就诊间MD的相关性(T1/T1 MD相关性r = 0.72,RMSE = 1.31)。在两次就诊中,从T1到T2,青光眼半视野测试中异常高敏感性率(3.2%对1.6%,P = 0.0023)和不可靠测试结果率(15.4%对9.2%,P = 0.002)均有显著的就诊内下降,同时MD(-I.28 dB对-1.68 dB,P<0.0001)和VF指数(P = 0.03)也相应显著下降。每次SFR测试的平均时长为132.6(标准差27.2)秒。

结论

使用SFR进行前置VF测试可产生可重复的视野数据组,从第一次测试到第二次测试,可靠性指标有显著改善。这可能有助于以最小的时间成本增加测试频率,以满足推荐指南要求,并用于评估易出现高变异性的患者。

财务披露

作者对本文中讨论的任何材料均无所有权或商业利益。

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