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卵巢未成熟畸胎瘤:放射学诊断线索。

Ovarian dysgerminoma: clues to the radiological diagnosis.

机构信息

Department of Radiology, Hospital do Divino Espírito Santo de Ponta Delgada.

Department of Pathology, Instituto Português de Oncologia de Lisboa Francisco Gentil.

出版信息

Diagn Interv Radiol. 2023 Jan 31;29(1):18-23. doi: 10.5152/dir.2022.21317. Epub 2022 Dec 21.

Abstract

Ovarian dysgerminoma (OD) is a rare germ cell tumor accounting for 1%-2% of all malignant ovarian tumors and is generally associated with a good prognosis. The condition is more frequent in young women and can arise in dysgenetic gonads that contain gonadoblastomas. While the definitive diagnosis of OD is only possible histologically, certain radiological features can provide facilitating clues. A large, unilateral, solid, lobulated ovarian tumor with markedly enhancing septa should raise the suspicion of OD in young women. Serum lactate dehydrogenase is characteristically elevated in this tumor type and can complement its diagnosis and postoperative follow-up; however, it is a nonspecific marker. Moreover, knowing the mimickers of OD is essential to optimizing the radiological image interpretation and allowing for adequate management and timely treatment. Therefore, in this article, the radiological and clinical-pathologic features of ODs were reviewed to allow radiologists to become familiarized with them and narrow the diagnostic possibilities when facing this type of tumor.

摘要

卵巢未成熟畸胎瘤(OD)是一种罕见的生殖细胞肿瘤,占所有恶性卵巢肿瘤的 1%-2%,通常预后良好。这种疾病在年轻女性中更为常见,可发生在含有性腺母细胞瘤的发育不良性腺中。虽然 OD 的明确诊断仅可通过组织学进行,但某些影像学特征可以提供辅助线索。在年轻女性中,单侧、大的、实性、分叶状卵巢肿瘤,伴有明显强化的间隔,应高度怀疑 OD。该肿瘤类型的血清乳酸脱氢酶通常升高,可补充其诊断和术后随访;然而,它是非特异性标志物。此外,了解 OD 的类似物对于优化影像学图像解释以及进行充分的管理和及时治疗至关重要。因此,本文回顾了 OD 的影像学和临床病理学特征,以使放射科医生熟悉这些特征,并在面对这种类型的肿瘤时缩小诊断可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e97f/10679589/ebbb947c9f4c/DIR-29-18-g1.jpg

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