Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona, USA.
Med Phys. 2023 Jun;50(6):3359-3367. doi: 10.1002/mp.16382. Epub 2023 Apr 6.
Mechanical accuracy should be verified before implementing a proton stereotactic radiosurgery (SRS) program. Linear accelerator (Linac)-based SRS systems often use electronic portal imaging devices (EPIDs) to verify beam isocentricity. Because proton therapy systems do not have EPID, beam isocentricity tests of proton SRS may still rely on films, which are not efficient.
To validate that our proton SRS system meets mechanical precision requirements and to present an efficient method to evaluate the couch and gantry's rotational isocentricity for our proton SRS system.
A dedicated applicator to hold brass aperture for proton SRS system was designed. The mechanical precision of the system was tested using a metal ball and film for 11 combinations of gantry and couch angles. A more efficient quality assurance (QA) procedure was developed, which used a scintillator device to replace the film. The couch rotational isocentricity tests were performed using orthogonal kV x-rays with the couch rotated isocentrically to five positions (0°, 315°, 270°, 225°, and 180°). At each couch position, the distance between the metal ball in kV images and the imaging isocenter was measured. The gantry isocentricity tests were performed using a cone-shaped scintillator and proton beams at five gantry angles (0°, 45°, 90°, 135°, and 180°), and the isocenter position and the distance of each beam path to the isocenter were obtained. Daily QA procedure was performed for 1 month to test the robustness and reproducibility of the procedure.
The gantry and couch rotational isocentricity exhibited sub-mm precision, with most measurements within ±0.5 mm. The 1-month QA results showed that the procedure was robust and highly reproducible to within ±0.2 mm. The gantry isocentricity test using the cone-shaped scintillator was accurate and sensitive to variations of ±0.2 mm. The QA procedure was efficient enough to be completed within 30 min. The 1-month isocentricity position variations were within 0.5 mm, which demonstrating that the overall proton SRS system was stable and precise.
The proton SRS Winston-Lutz QA procedure using a cone-shaped scintillator was efficient and robust. We were able to verify radiation delivery could be performed with sub-mm mechanical precision.
在实施质子立体定向放射外科(SRS)计划之前,应验证机械精度。基于直线加速器(Linac)的 SRS 系统通常使用电子射野影像装置(EPID)来验证射束等中心性。由于质子治疗系统没有 EPID,质子 SRS 的射束等中心性测试可能仍然依赖于胶片,这不是一种有效的方法。
验证我们的质子 SRS 系统满足机械精度要求,并提出一种高效的方法来评估我们的质子 SRS 系统的治疗床和旋转等中心性。
设计了一个专用的适形器来固定用于质子 SRS 系统的黄铜孔径。使用金属球和胶片对 11 种机架和治疗床角度组合进行了系统机械精度测试。开发了一种更有效的质量保证(QA)程序,该程序使用闪烁体设备代替胶片。使用正交千伏 X 射线旋转治疗床至五个位置(0°、315°、270°、225°和 180°),以等中心方式进行治疗床旋转等中心性测试。在每个治疗床位置,测量千伏图像中的金属球与成像等中心之间的距离。使用锥形闪烁体和五个机架角度(0°、45°、90°、135°和 180°)的质子束进行机架等中心性测试,并获得等中心位置和每条射束路径到等中心的距离。进行了为期一个月的日常 QA 程序,以测试该程序的稳健性和可重复性。
机架和治疗床旋转等中心性表现出亚毫米精度,大多数测量值在±0.5mm 以内。一个月的 QA 结果表明,该程序非常稳健,可重复性高,误差在±0.2mm 以内。使用锥形闪烁体的机架等中心性测试准确且对±0.2mm 的变化敏感。QA 程序的效率足够高,可以在 30 分钟内完成。一个月的等中心位置变化在 0.5mm 以内,这表明整个质子 SRS 系统稳定且精确。
使用锥形闪烁体的质子 SRS Winston-Lutz QA 程序高效且稳健。我们能够验证辐射传输可以达到亚毫米级的机械精度。