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使用电影式电子射野影像系统和弧形照射验证立体定向放射外科的直线加速器等中心位置

Verification of the linac isocenter for stereotactic radiosurgery using cine-EPID imaging and arc delivery.

机构信息

School of Mathematical and Physical Sciences, University of Newcastle, Newcastle, New South Wales 2308, Australia.

出版信息

Med Phys. 2011 Jul;38(7):3963-70. doi: 10.1118/1.3597836.

Abstract

PURPOSE

Verification of the mechanical isocenter position is required as part of comprehensive quality assurance programs for stereotactic radiosurgery/radiotherapy (SRS/SRT) treatments. Several techniques have been proposed for this purpose but each of them has certain drawbacks. In this paper, a new efficient and more comprehensive method using cine-EPID images has been introduced for automatic verification of the isocenter with sufficient accuracy for stereotactic applications.

METHODS

Using a circular collimator fixed to the gantry head to define the field, EPID images of a Winston-Lutz phantom were acquired in cine-imaging mode during 3600 gantry rotations. A robust MATLAB code was developed to analyze the data by finding the center of the field and the center of the ball bearing shadow in each image with sub-pixel accuracy. The distance between these two centers was determined for every image. The method was evaluated by comparison to results of a mechanical pointer and also by detection of a manual shift applied to the phantom position. The repeatability and reproducibility of the method were tested and it was also applied to detect couch and collimator wobble during rotation.

RESULTS

The accuracy of the algorithm was 0.03 +/- 0.02 mm. The repeatability was less than 3 pm and the reproducibility was less than 86 microm. The time elapsed for the analysis of more than 100 cine images of Varian aS1000 and aS500 EPIDs were approximately 65 and 20 s, respectively. Processing of images taken in integrated mode took 0.1 s. The output of the analysis software is printable and shows the isocenter shifts as a function of angle in both in-plane and cross-plane directions. It gives warning messages where the shifts exceed the criteria for SRS/SRT and provides useful data for the necessary adjustments in the system including bearing system and/or room lasers.

CONCLUSIONS

The comprehensive method introduced in this study uses cine-images, is highly accurate, fast, and independent of the observer. It tests all gantry angles and is suitable for pretreatment QA of the isocenter for stereotactic treatments.

摘要

目的

作为立体定向放射外科/放疗(SRS/SRT)治疗综合质量保证计划的一部分,需要验证机械等中心位置。为此目的已经提出了几种技术,但每种技术都有一定的缺点。本文介绍了一种新的、更有效的方法,该方法使用电影 EPID 图像,以足够的立体定向应用精度自动验证等中心。

方法

使用固定在机架头部的圆形准直器来定义射野,在机架旋转 3600 度的过程中,以电影成像模式采集 Winston-Lutz 体模的 EPID 图像。开发了一个强大的 MATLAB 代码,通过亚像素精度在每张图像中找到射野中心和球轴承阴影中心,来分析数据。为每张图像确定这两个中心之间的距离。该方法通过与机械指针的结果进行比较,以及通过检测幻影位置的手动移位进行评估。测试了该方法的重复性和可再现性,并将其应用于检测旋转过程中的治疗床和准直器摆动。

结果

该算法的精度为 0.03 +/- 0.02 毫米。重复性小于 3 微米,可再现性小于 86 微米。分析超过 100 张瓦里安 aS1000 和 aS500 EPID 的电影图像所花费的时间分别约为 65 和 20 秒。处理集成模式下的图像需要 0.1 秒。分析软件的输出是可打印的,并显示等中心在平面内和横向上的角度的移位。当移位超过 SRS/SRT 的标准时,它会发出警告信息,并为系统的必要调整提供有用的数据,包括轴承系统和/或房间激光。

结论

本研究中介绍的综合方法使用电影图像,具有高度准确性、快速性和不依赖于观察者的特点。它测试所有机架角度,适用于立体定向治疗的等中心治疗前 QA。

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