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一项关于在两种不同的电子射野影像装置上进行温斯顿-卢茨测试以及低能量成像的研究。

A study of Winston-Lutz test on two different electronic portal imaging devices and with low energy imaging.

作者信息

Ravindran Paul B

机构信息

Department of Radiation Oncology, The Brunei Cancer Center, Bandar Seri Begawan, Brunei Darussalam.

Faculty of Science, University of Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam.

出版信息

Australas Phys Eng Sci Med. 2016 Sep;39(3):677-85. doi: 10.1007/s13246-016-0463-9. Epub 2016 Jul 19.

Abstract

Stereotactic radiosurgery requires sub-millimetre accuracy in patient positioning and target localization. Therefore, verification of the linear accelerator (linac) isocentre and the laser alignment to the isocentre is performed in some clinics prior to the treatment using the Winston-Lutz (W-L) test with films and more recently with images obtained using the electronic portal imaging devices (EPID). The W-L test is performed by acquiring EPID images of a radio-opaque ball of 6 mm diameter (the W-L phantom) placed at the isocentre of the linac at various gantry and table angles, with a predefined small square or circular radiation beam. In this study, the W-L test was performed on two linacs having EPIDs of different size and resolution, viz, a TrueBeam™ linac with aS1000 EPID of size 40 × 30 cm(2) with 1024 × 768 pixel resolution and an EDGE™ linac having an EPID of size 43 × 43 cm(2) with pixel resolution of 1280 × 1280. In order to determine the displacement of the radio-opaque ball centre from the radiation beam centre of the W-L test, an in-house MATLAB™ image processing code was developed using morphological operations. The displacement in radiation beam centre at each gantry and couch position was obtained by determining the distance between the radiation field centre and the radio-opaque ball centre for every image. Since the MATLAB code was based on image processing that was dependent on the image contrast and resolution, the W-L test was also compared for images obtained with different beam energies. The W-L tests were performed for 6 and 8 MV beams on the TrueBeam™ linac and for 2.5 and 6 MV beams on the EDGE™ linac with a higher resolution EPID. It was observed that the images obtained with the EPID of higher resolution resulted in same accuracy in the determination of the displacement between the centres of the radio-opaque ball and the radiation beam, and significant difference was not observed with images acquired with different energies. It is concluded that the software based on morphological operations provided an accurate estimation of the displacement of the ball centre from the radiation beam center.

摘要

立体定向放射外科手术要求患者定位和靶区定位的精度达到亚毫米级。因此,在一些诊所,在治疗前会使用温斯顿 - 卢茨(W-L)测试(使用胶片,最近也使用电子射野影像装置(EPID)获取的图像)来验证直线加速器(直线加速器)等中心以及激光与等中心的对准情况。W-L测试是通过在直线加速器等中心放置一个直径6毫米的不透射线球(W-L体模),在不同的机架和治疗床角度,使用预定义的小方形或圆形辐射束,采集EPID图像来进行的。在本研究中,对两台配备不同尺寸和分辨率EPID的直线加速器进行了W-L测试,即一台配备尺寸为40×30 cm²、像素分辨率为1024×768的aS1000 EPID的TrueBeam™直线加速器,以及一台配备尺寸为43×43 cm²、像素分辨率为1280×1280的EPID的EDGE™直线加速器。为了确定不透射线球中心相对于W-L测试辐射束中心的位移,使用形态学运算开发了一个内部MATLAB™图像处理代码。通过确定每个图像中辐射野中心与不透射线球中心之间的距离,获得每个机架和治疗床位置处辐射束中心的位移。由于MATLAB代码基于依赖图像对比度和分辨率的图像处理,还对不同束能量下获得的图像进行了W-L测试比较。在TrueBeam™直线加速器上对6和8 MV束进行了W-L测试,在EDGE™直线加速器上对2.5和6 MV束进行了具有更高分辨率EPID的W-L测试。观察到,使用更高分辨率的EPID获得的图像在确定不透射线球中心与辐射束中心之间的位移时具有相同的精度,并且不同能量采集的图像之间未观察到显著差异。得出的结论是,基于形态学运算的软件能够准确估计球中心相对于辐射束中心的位移。

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