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基于 NHANES 2009-2018 数据,从人口统计学特征、身体指标和生活习惯角度探讨美国糖尿病的流行情况。

Prevalence of diabetes in the USA from the perspective of demographic characteristics, physical indicators and living habits based on NHANES 2009-2018.

机构信息

Shaanxi Key Laboratory of Chinese Medicine Encephalopathy, Shaanxi University of Chinese Medicine, Xianyang, China.

Department of Laboratory Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China.

出版信息

Front Endocrinol (Lausanne). 2023 Mar 7;14:1088882. doi: 10.3389/fendo.2023.1088882. eCollection 2023.

Abstract

OBJECTIVE

To determine differences in DM in the U.S. population according to demographic characteristics, physical indicators and living habits.

METHODS

23 546 participants in the 2009 to 2018 National Health and Nutrition Examination Survey (NHANES) who were 20 year of age or older and not pregnant. All analyses used weighted samples and considered the stratification and clustering of the design. Specific indicators include length of leg (cm), BMI (kg/cm), TCHOL (mg/dL), fasting plasma glucose (mg/dL) and comparison of means and the proportion of participants with DM.

RESULTS

The prevalence of DM in the USA has been rising modestly in the past decade, and were consistent and robust for the observed differences in age, sex, and ethnicity. Compared with white participants, black participants and Mexican-American were both more likely (P<0.001) to have diabetes: 14.6% (CI, 13.6% to 15.6%) among black participants, 10.6% (CI, 9.9% to 11.3%) among white participants, and 13.5% (CI, 11.9% to 15.2%) among Mexican-American participants. The prevalence of diabetes is increasing with age, males peaked around the 60s, and women around the 70s. The overall mean leg length and TCHOL was lower in diabetics than in non-diabetics (1.07 cm, 18.67 mg/dL, respectively), while mean BMI were higher in diabetics than in non-diabetics (4.27 kg/cm2). DM had the greatest effect on decline of TCHOL in white participants (23.6 mg/dL), less of an effect in black participants (9.67 mg/dL), and the least effect in Mexican-American participants (8.25 mg/dL). Notably, smoking had great effect on percent increment of DM in whites (0.2%), and have little effect on black and Mexican-Americans.

CONCLUSIONS

DM is more common in the general population than might be clinically recognized, and the prevalence of DM was associated to varying degrees with many indicators of demographic characteristics, physical indicators, and living habits. These indicators should be linked with medical resource allocation and scientific treatment methods to comprehensively implement the treatment of DM.

摘要

目的

根据人口统计学特征、身体指标和生活习惯,确定美国人群中的糖尿病差异。

方法

2009 年至 2018 年全国健康和营养调查(NHANES)中 20 岁及以上且未怀孕的 23546 名参与者。所有分析均使用加权样本,并考虑了设计的分层和聚类。具体指标包括腿长(cm)、BMI(kg/cm)、总胆固醇(mg/dL)、空腹血糖(mg/dL)以及均值和参与者中糖尿病比例的比较。

结果

在过去十年中,美国的糖尿病患病率呈适度上升趋势,且在观察到的年龄、性别和种族差异方面具有一致性和稳健性。与白人参与者相比,黑人参与者和墨西哥裔美国人患糖尿病的可能性更高(P<0.001):黑人参与者中为 14.6%(95%CI,13.6%至 15.6%),白人参与者中为 10.6%(95%CI,9.9%至 11.3%),墨西哥裔美国人参与者中为 13.5%(95%CI,11.9%至 15.2%)。糖尿病的患病率随着年龄的增长而增加,男性在 60 多岁时达到峰值,女性在 70 多岁时达到峰值。糖尿病患者的总体平均腿长和总胆固醇低于非糖尿病患者(分别为 1.07cm 和 18.67mg/dL),而糖尿病患者的平均 BMI 高于非糖尿病患者(4.27kg/cm2)。糖尿病对白人参与者总胆固醇的降低影响最大(23.6mg/dL),对黑人参与者的影响较小(9.67mg/dL),对墨西哥裔美国人参与者的影响最小(8.25mg/dL)。值得注意的是,吸烟对白人中糖尿病百分比的增加影响很大(0.2%),对黑人和墨西哥裔美国人的影响很小。

结论

糖尿病在普通人群中比临床上可能认识到的更为常见,糖尿病的患病率与人口统计学特征、身体指标和生活习惯的许多指标都有不同程度的关联。这些指标应与医疗资源分配和科学治疗方法联系起来,以全面实施糖尿病的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13fb/10028205/6858dd8b60cf/fendo-14-1088882-g001.jpg

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