Computer Science Department, University of Tabriz, Tabriz, Iran.
Maternal, Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
PLoS One. 2023 Mar 24;18(3):e0263991. doi: 10.1371/journal.pone.0263991. eCollection 2023.
The 2019 newfound Coronavirus (COVID-19) still remains as a threatening disease of which new cases are being reported daily from all over the world. The present study aimed at estimating the related rates of morbidity, growth, and mortality for COVID-19 over a three-month period starting from Feb, 19, 2020 to May 18, 2020 in Iran. In addition, it revealed the effect of the mean age, changes in weather temperature and country's executive policies including social distancing, restrictions on travel, closing public places, shops and educational centers. We have developed a combined neural network to estimate basic reproduction number, growth, and mortality rates of COVID-19. Required data was obtained from daily reports of World Health Organization (WHO), Iran Meteorological Organization (IRIMO) and the Statistics Center of Iran. The technique used in the study encompassed the use of Artificial Neural Network (ANN) combined with Swarm Optimization (PSO) and Bus Transportation Algorithms (BTA). The results of the present study showed that the related mortality rate of COVID-19 is in the range of [0.1], and the point 0.275 as the mortality rate provided the best results in terms of the total training and test squared errors of the network. Furthermore, the value of basic reproduction number for ANN-BTA and ANN-PSO was 1.045 and 1.065, respectively. In the present study, regarding the closest number to the regression line (0.275), the number of patients was equal to 2566200 cases (with and without clinical symptoms) and the growth rate based on arithmetic means was estimated to be 1.0411 and 1.06911, respectively. Reviewing the growth and mortality rates over the course of 90 days, after 45 days of first case detection, the highest increase in mortality rate was reported 158 cases. Also, the highest growth rate was related to the eighth and the eighteenth days after the first case report (2.33). In the present study, the weather variant in relationship to the basic reproduction number and mortality rate was estimated ineffective. In addition, the role of quarantine policies implemented by the Iranian government was estimated to be insignificant concerning the mortality rate. However, the age range was an ifluential factor in mortality rate. Finally, the method proposed in the present study cofirmed the role of the mean age of the country in the mortality rate related to COVID-19 patients at the time of research conduction. The results indicated that if sever quarantine restrictions are not applied and Iranian government does not impose effective interventions, about 60% to 70% of the population (it means around 49 to 58 million people) would be afflicted by COVID-19 during June to September 2021.
2019 年新型冠状病毒(COVID-19)仍然是一种威胁性疾病,每天都有新的病例在世界各地报告。本研究旨在估计从 2020 年 2 月 19 日至 5 月 18 日开始的三个月内 COVID-19 的发病率、增长率和死亡率相关比率,在伊朗。此外,它揭示了平均年龄、天气温度变化以及包括社会隔离、旅行限制、关闭公共场所、商店和教育中心在内的国家执行政策的影响。我们开发了一种组合神经网络来估计 COVID-19 的基本繁殖数、增长率和死亡率。所需数据来自世界卫生组织(世卫组织)、伊朗气象组织(IRIMO)和伊朗统计中心的每日报告。该研究中使用的技术包括使用人工神经网络(ANN)与群体智能优化(PSO)和公共汽车运输算法(BTA)相结合。本研究的结果表明,COVID-19 的相关死亡率在[0.1]范围内,死亡率为 0.275 是网络总训练和测试平方误差的最佳结果。此外,ANN-BTA 和 ANN-PSO 的基本繁殖数分别为 1.045 和 1.065。在本研究中,关于最接近回归线的数字(0.275),患者人数等于 2566200 例(有和无症状),基于算术平均值的增长率估计分别为 1.0411 和 1.06911。回顾 90 天内的增长率和死亡率,在首次病例检测后 45 天,死亡率报告最高增加 158 例。此外,第八天和第十八天的增长率最高,首次报告后(2.33)。在本研究中,天气变量与基本繁殖数和死亡率之间的关系被认为无效。此外,伊朗政府实施的检疫政策对死亡率的影响被认为是微不足道的。然而,年龄范围是死亡率的一个影响因素。最后,本研究提出的方法证实了该国的平均年龄在研究期间与 COVID-19 患者死亡率有关。结果表明,如果不实施严格的检疫限制,伊朗政府不采取有效干预措施,大约 60%至 70%的人口(即约 4900 万至 5800 万人)将在 2021 年 6 月至 9 月期间感染 COVID-19。