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[胰腺部分切除术后升压和降压反应的变化]

[Changes in pressor and depressor reactions following partial pancreatectomy].

作者信息

Rzaev N M, Abaskulieva L I, Khanumova T A

出版信息

Biull Eksp Biol Med. 1979 Feb;87(2):103-6.

PMID:369634
Abstract

Experiments were conducted on 39 mongrel pubertal dogs. The course of pressor and depressor reactions under conditions of normal vital activity and after partial corporocaudal resection of the pancreas was studied. The principal indices characterizing the changes of pressor reaction to noradrenaline, and of the depressor one -- to bradykinin and kallikrein before and 10 to 12 days after the corporocaudal resection of the pancreas were determined. Resection of the corporo-caudal part of the pancreas intensified the pressor reactions to noradrenaline, and depressor ones to bradykinin and kallikrein; it increased the initial negative chronotropic effect of catecholamines on the heart, and also enhanced the positive chronotropic effect of noradrenaline, kallikrein and bradykinin on the heart.

摘要

对39只杂种青春期犬进行了实验。研究了正常生命活动条件下以及胰腺体尾部部分切除后升压和降压反应的过程。测定了胰腺体尾部切除术前及术后10至12天,表征对去甲肾上腺素升压反应以及对缓激肽和激肽释放酶降压反应变化的主要指标。胰腺体尾部切除增强了对去甲肾上腺素的升压反应,以及对缓激肽和激肽释放酶的降压反应;它增加了儿茶酚胺对心脏最初的负性变时作用,同时也增强了去甲肾上腺素、激肽释放酶和缓激肽对心脏的正性变时作用。

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