Chow C B, Wang P S, Cheung M W, Yan W W, Leung N K
Paediatric A Unit, Princess Margaret Hospital, Hong Kong.
Pediatr Infect Dis J. 1987 Oct;6(10):914-7. doi: 10.1097/00006454-198710000-00011.
The usefulness of the Widal test in diagnosing childhood typhoid fever in endemic areas was investigated. The test was done on 150 children with other febrile illnesses and 98 bacteriologically proved cases of typhoid fever. Of the 150 children with nontyphoidal fever, only one had an H agglutinin titer of 1:50. Using an H or O agglutinin titer of 1:50 or more as a criterion for diagnosis, a positive Widal test was found in 88% of typhoid fever cases on the first occasion on which the test was done. If the test was repeated at least 94% of the typhoid cases had a significant result. The Widal test is a useful diagnostic test in children in endemic areas, provided interpretation of the test is made against background information relating to agglutinin levels in normal children in the region.
研究了肥达试验在流行地区诊断儿童伤寒热中的实用性。对150名患有其他发热性疾病的儿童以及98例经细菌学证实的伤寒热病例进行了该试验。在150名非伤寒热儿童中，只有一名的H凝集素效价为1:50。以H或O凝集素效价1:50及以上作为诊断标准，首次进行肥达试验时，88%的伤寒热病例试验呈阳性。如果重复进行该试验，至少94%的伤寒病例会有显著结果。在流行地区，肥达试验对儿童是一种有用的诊断试验，前提是根据该地区正常儿童凝集素水平的背景信息对试验结果进行解读。
