Somerville P C, Lewis M, Koornhof H J, Alberts M, Alberts H W, Raymond R
S Afr Med J. 1981 Jun 6;59(24):851-4.
We analysed the results of the Widal test in the northern and eastern Transvaal in relation to bacteriologically confirmed cases of typhoid fever, patients suspected of having the disease, febrile patients without typhoid fever and healthy individuals. Titres of 1:200 or greater for either H or O agglutinins were recorded for 75,2% of patients with bacteriologically proven typhoid fever, 4,6% of healthy subjects residing in an endemic area and 7,5% of patients presenting with non-thyroid fevers. Age, sex and region were found to affect the percentage of positive tests recorded. Despite these failings, the Widal test was found to be of value in the diagnosis of typhoid fever. The concept of a diagnostic titre was considered unreliable, but considered in conjunction with the clinical picture, O or H agglutinin titres of 1:200 or more may be regarded as strong presumptive evidence of typhoid fever.
我们分析了德兰士瓦省北部和东部地区维达试验的结果，这些结果与经细菌学确诊的伤寒病例、疑似患有该病的患者、无伤寒热的发热患者以及健康个体相关。在经细菌学证实的伤寒热患者中，75.2%的患者H或O凝集素滴度达到1:200或更高；在地方性流行区居住的健康受试者中，这一比例为4.6%；在出现非伤寒热的患者中，这一比例为7.5%。研究发现年龄、性别和地区会影响检测呈阳性的百分比。尽管存在这些不足之处，但维达试验在伤寒热的诊断中仍具有价值。诊断滴度的概念被认为不可靠，但结合临床表现来看，O或H凝集素滴度达到1:200或更高可被视为伤寒热的有力推定证据。
