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新生儿重症监护病房(NICU)中的高血压:一例中主动脉综合征病例

Hypertension in the Neonatal Intensive Care Unit (NICU): A Case of Mid-Aortic Syndrome.

作者信息

Ropri Ayesha, Randall Jess

机构信息

Internal Medicine/Pediatrics, Albany Medical Center, Albany, USA.

Pediatrics, Albany Medical Center, Albany, USA.

出版信息

Cureus. 2023 Feb 21;15(2):e35282. doi: 10.7759/cureus.35282. eCollection 2023 Feb.

DOI:10.7759/cureus.35282
PMID:36968885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10036239/
Abstract

A term baby was born with findings of edema, harsh murmur, and hypertension. Pregnancy course was complicated by hydrops fetalis. Upon birth, blood work did not reveal any abnormalities, but an echocardiogram showed patient in high-output heart failure. A computed tomography (CT) chest, abdomen, and pelvis revealed narrowing of aorta in the thoracic region to distal iliac and renal arteries, consistent with mid-aortic syndrome. Mid-aortic syndrome, which results in the narrowing of thoracic or abdominal aorta, is a rare cause of hypertension, especially in newborns. This case elucidates the importance of maintaining a broad differential when encountering an uncommon problem in a newborn.

摘要

一名足月儿出生时出现水肿、粗糙杂音和高血压。孕期过程并发胎儿水肿。出生时,血液检查未发现任何异常,但超声心动图显示患儿处于高输出量心力衰竭状态。胸部、腹部和骨盆的计算机断层扫描(CT)显示胸段主动脉至髂动脉远端和肾动脉变窄,符合中段主动脉综合征。中段主动脉综合征导致胸主动脉或腹主动脉变窄,是高血压的罕见原因,尤其是在新生儿中。该病例阐明了在新生儿中遇到不常见问题时保持广泛鉴别诊断的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cfb/10036239/ed36f95ae530/cureus-0015-00000035282-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cfb/10036239/ed36f95ae530/cureus-0015-00000035282-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cfb/10036239/ed36f95ae530/cureus-0015-00000035282-i01.jpg

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本文引用的文献

1
Diagnosis and Management of Genetic Causes of Middle Aortic Syndrome in Children: A Comprehensive Literature Review.儿童中段主动脉综合征遗传病因的诊断与管理:一项全面的文献综述
Ther Clin Risk Manag. 2022 Mar 16;18:233-248. doi: 10.2147/TCRM.S348366. eCollection 2022.
2
Midaortic syndrome in a middle-age female.中年女性的中段主动脉综合征。
BMJ Case Rep. 2021 Nov 9;14(11):e246530. doi: 10.1136/bcr-2021-246530.
3
Surgical management of pediatric renovascular hypertension and midaortic syndrome at a single-center multidisciplinary program.
单中心多学科项目中小儿肾血管性高血压和中主动脉综合征的外科治疗。
J Vasc Surg. 2021 Jul;74(1):79-89.e2. doi: 10.1016/j.jvs.2020.12.053. Epub 2020 Dec 16.
4
Neonatal Hypertension.新生儿高血压
Pediatr Rev. 2020 Jun;41(6):307-311. doi: 10.1542/pir.2019-0159.
5
Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents.临床实践指南:儿童和青少年高血压的筛查和管理。
Pediatrics. 2017 Sep;140(3). doi: 10.1542/peds.2017-1904. Epub 2017 Aug 21.
6
Mid-Aortic Syndrome in a Preterm Infant: A Rare Cause of Hypertension.一名早产儿的主动脉中段综合征:高血压的罕见病因。
J Pediatr. 2015 Aug;167(2):492-e1. doi: 10.1016/j.jpeds.2015.05.007. Epub 2015 May 30.
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Disease Beyond the Arch: A Systematic Review of Middle Aortic Syndrome in Childhood.主动脉弓外疾病:儿童中主动脉综合征的系统评价
Am J Hypertens. 2015 Jul;28(7):833-46. doi: 10.1093/ajh/hpu296. Epub 2015 Jan 27.
8
Midaortic syndrome: 30 years of experience with medical, endovascular and surgical management.巨主动脉综合征:30 年的医疗、血管内和手术治疗经验。
Pediatr Nephrol. 2013 Oct;28(10):2023-33. doi: 10.1007/s00467-013-2514-8. Epub 2013 Jun 18.
9
Mid-aortic syndrome in two preterm infants.两名早产儿的中主动脉综合征。
J Perinatol. 2012 May;32(5):390-2. doi: 10.1038/jp.2011.130.
10
Mid-aortic syndrome: long-term outcome of 36 children.中段主动脉综合征:36例儿童的长期预后
Pediatr Nephrol. 2009 Nov;24(11):2225-32. doi: 10.1007/s00467-009-1242-6. Epub 2009 Jul 15.