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用于增强肿瘤免疫治疗效果的中药活性成分。

Active ingredients of traditional Chinese medicine for enhancing the effect of tumor immunotherapy.

机构信息

National Engineering Research Center for Marine Aquaculture, Institute of Innovation & Application, Zhejiang Ocean University, Zhoushan, Zhejiang, China.

State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

出版信息

Front Immunol. 2023 Mar 10;14:1133050. doi: 10.3389/fimmu.2023.1133050. eCollection 2023.

Abstract

Immunotherapy is a type of treatment that uses our own immune system to fight cancer. Studies have shown that traditional Chinese medicine (TCM) has antitumor activity and can enhance host immunity. This article briefly describes the immunomodulatory and escape mechanisms in tumors, as well as highlights and summarizes the antitumor immunomodulatory activities of some representative active ingredients of TCM. Finally, this article puts forward some opinions on the future research and clinical application of TCM, aiming to promote the clinical applications of TCM in tumor immunotherapy and to provide new ideas for the research of tumor immunotherapy using TCM.

摘要

免疫疗法是一种利用我们自身免疫系统来对抗癌症的治疗方法。研究表明,中医药具有抗肿瘤活性,能够增强机体免疫力。本文简要描述了肿瘤中的免疫调节和逃逸机制,并重点总结了一些具有代表性的中医药活性成分的抗肿瘤免疫调节作用。最后,本文对中医药未来的研究和临床应用提出了一些意见,旨在促进中医药在肿瘤免疫治疗中的临床应用,并为中医药在肿瘤免疫治疗研究方面提供新的思路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1214/10036358/44403cb7d75b/fimmu-14-1133050-g001.jpg

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