State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
College of Animal Science, Zhejiang A&F University, Hangzhou, China.
Front Immunol. 2023 Mar 9;14:1142915. doi: 10.3389/fimmu.2023.1142915. eCollection 2023.
This study was conducted to assess the effects of dietary supplementation of coated sodium butyrate (CSB) on the growth performance, serum antioxidant, immune performance, and intestinal microbiota of laying ducks.
A total of 120 48-week-old laying ducks were randomly divided into 2 treatment groups: the control group (group C fed a basal diet) and the CSB-treated group (group CSB fed the basal diet + 250 g/t of CSB). Each treatment consisted of 6 replicates, with 10 ducks per replicate, and the trial was conducted for 60 days.
Compared with the group C, the group CSB showed a significant increase in the laying rate (p<0.05) of the 53-56 week-old ducks. Additionally, the serum total antioxidant capacity, superoxide dismutase activity and immunoglobulin G level were significantly higher (p<0.05), while the serum malondialdehyde content and tumor necrosis factor (TNF)-a level were significantly lower (p<0.05) in the serum of the group CSB compared to the group C. Moreover, the expression of IL-1b and TNF-a in the spleen of the group CSB was significantly lower (p<0.05) compared to that of the group C. In addition, compared with the group C, the expression of Occludin in the ileum and the villus height in the jejunum were significantly higher in the group CSB (p<0.05). Furthermore, Chao1, Shannon, and Pielou-e indices were higher in the group CSB compared to the group C (p<0.05). The abundance of Bacteroidetes in the group CSB was lower than that in the group C (p<0.05), while the abundances of Firmicutes and Actinobacteria were higher in the group CSB compared to the group C (p<0.05).
Our results suggest that the dietary supplementation of CSB can alleviate egg-laying stress in laying ducks by enhancing immunity and maintaining the intestinal health of the ducks.
本研究旨在评估包膜丁酸钠（CSB）的膳食补充对产蛋鸭生长性能、血清抗氧化、免疫性能和肠道微生物群的影响。
将 120 只 48 周龄产蛋鸭随机分为 2 个处理组：对照组（C 组，饲喂基础日粮）和 CSB 处理组（CSB 组，饲喂基础日粮+250 g/t CSB）。每个处理组包含 6 个重复，每个重复 10 只鸭，试验期为 60 天。
与 C 组相比，CSB 组 53-56 周龄鸭的产蛋率显著提高（p<0.05）。此外，CSB 组血清总抗氧化能力、超氧化物歧化酶活性和免疫球蛋白 G 水平显著升高（p<0.05），血清丙二醛含量和肿瘤坏死因子（TNF）-a 水平显著降低（p<0.05）。此外，CSB 组脾脏中 IL-1b 和 TNF-a 的表达显著低于 C 组（p<0.05）。此外，与 C 组相比，CSB 组回肠 Occludin 的表达和空肠绒毛高度显著升高（p<0.05）。此外，CSB 组的 Chao1、Shannon 和 Pielou-e 指数均高于 C 组（p<0.05）。CSB 组厚壁菌门的丰度低于 C 组（p<0.05），而 CSB 组的 Firmicutes 和 Actinobacteria 的丰度高于 C 组（p<0.05）。
本研究结果表明，日粮中添加 CSB 可以通过增强免疫力和维持鸭的肠道健康来缓解产蛋鸭的产蛋压力。
