Park Jeong-Hui, Prochnow Tyler, Chang Jongwha, Kim Sun Jung
Texas A&M University, School of Public Health, College Station, TX, USA.
Texas A&M University, Irma Lerma Rangel School of Pharmacy, College Station, TX, USA.
Patient Prefer Adherence. 2023 Mar 18;17:739-747. doi: 10.2147/PPA.S406125. eCollection 2023.
Atopic dermatitis (AD) is one of the common chronic diseases that occur in children and adolescents as a chronic relapsing pruritic inflammatory skin disease. This study investigated how AD is associated with stress and depressive symptoms in a large representative sample of adolescents in South Korea.
The Korea Youth Risk Behavior Web-based Survey 2019 was used in this study (n = 57,069, weighted national estimates = 2,672,170). Multivariate logistic regression was used to determine significant associations between AD and mental health, measured by stress and depressive symptoms. Sub-group analysis was also conducted using various socio-economic variables.
Among the present sample, 6.5% of adolescents (n = 173,909) were diagnosed with AD in the past 12 months. After adjusting for other variables, AD diagnosis was associated with significantly higher odds of experiencing stress (OR = 1.43) and depressive symptoms (OR = 1.32) as compared to adolescents without AD. A similar trend is found in subgroup model analysis using socio-economic variables (ie, education levels, parent's income levels, and residence area). Specifically, female adolescents with AD, adolescents of low socio-economic status, those reporting smoking and drinking experience, and who do not participate in regular physical activity are more vulnerable to stress and depressive symptoms.
This is a noteworthy finding because it denotes that AD may lead to negative outcomes, like depressive symptoms or stress, which could be prevented if suspected early.
特应性皮炎(AD)是儿童和青少年中常见的慢性疾病之一,是一种慢性复发性瘙痒性炎症性皮肤病。本研究调查了在韩国具有广泛代表性的青少年样本中,AD与压力和抑郁症状之间的关联。
本研究使用了2019年韩国青少年风险行为网络调查(n = 57,069,加权全国估计数 = 2,672,170)。采用多因素逻辑回归分析来确定AD与以压力和抑郁症状衡量的心理健康之间的显著关联。还使用各种社会经济变量进行了亚组分析。
在当前样本中,6.5%的青少年(n = 173,909)在过去12个月内被诊断患有AD。在对其他变量进行调整后,与未患AD的青少年相比,AD诊断与经历压力(OR = 1.43)和抑郁症状(OR = 1.32)的几率显著更高相关。在使用社会经济变量(即教育水平、父母收入水平和居住地区)的亚组模型分析中也发现了类似趋势。具体而言,患有AD的女性青少年、社会经济地位低的青少年、报告有吸烟和饮酒经历的青少年以及不参加定期体育活动的青少年更容易出现压力和抑郁症状。
这是一个值得注意的发现,因为它表明AD可能导致负面结果,如抑郁症状或压力,如果早期怀疑则可以预防。